×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
KIT 抗体 (pTyr936)
KIT
适用: 人
IHC (p)
宿主: 兔
Polyclonal
unconjugated
KIT抗体详情
(hide)
抗原
See all KIT 抗体
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
抗原表位
All epitopes for KIT 抗体
pTyr936
适用
All reactivities for KIT 抗体
人
宿主
All hosts for KIT 抗体
兔
克隆类型
All clonalities for KIT 抗体
多克隆
标记
All conjugates for KIT 抗体
This KIT antibody is un-conjugated
应用范围
All applications for KIT 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
C-kit (phospho-Tyr936) Antibody AP08039PU detects endogenous levels of c-kit only when phosphorylated at Tyrosine 936.
纯化方法
Immunoaffinity Chromatography.
免疫原
The antiserum was produced against synthesized phosphopeptide derived from human c- kit around the phosphorylation site of Tyrosine 936 (H-I-YP-S-N).
Top Product
Discover our top product KIT Primary Antibody
Alternatives
(show)
使用细节
(hide)
应用备注
Immunohistochemistry (1/50-1/100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
(hide)
缓冲液
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Store the antibody (in aliquots) at-20 °C.
KIT目标详情
(hide)
抗原
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
别名
CD117 / C-Kit (KIT 产品 )
别名
C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
背景
C-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR
基因ID
3815
NCBI登录号
NP_000213
UniProt
P10721
途径
RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Sensory Perception of Sound , Stem Cell Maintenance , Production of Molecular Mediator of Immune Response , Regulation of long-term Neuronal Synaptic Plasticity
Recently viewed
(hide)