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CD44 抗体

CD44 适用: 人 IHC (fro) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN318928
发货至: 中国
  • 抗原 See all CD44 抗体
    CD44
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    宿主
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    山羊
    克隆类型
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    多克隆
    标记
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    This CD44 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody specifically recognises epitopes encoded by exons v3-v10 on the variant portion of CD44.
    纯化方法
    Purified
    免疫原
    Recombinant human CD44v3-v10
    亚型
    IgG
    Top Product
    Discover our top product CD44 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections: 50g/mL. Immunohistochemistry on paraffin sections: 20g/mL, requires antigen retrieval using heattreatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 isrecommended for this purpose. Positive Control: Breast carcinoma and colon adenocarcinoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0mg/mL
    缓冲液
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD44
    别名
    CD44 (CD44 产品)
    别名
    CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody
    背景
    CD44 is a ubiquitously expressed type 1 transmembrane glycoprotein and proteoglycan, otherwise known as phagocytic glycoprotein 1 (pgp 1), which acts as a receptor for the major extracellular matrix component hyaluronate, and also binds other ligands including collagen and matrix metalloproteinases (MMPs). CD44 is known to play a role in cell-cell interactions, cell adhesion, the activation and homing of lymphocytes, cell migration, haematopoiesis and metastasis, and exists as a number of isoforms generated by the alternative RNA splicing of at least 10 variant exons (CD44v).Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I
    基因ID
    960
    NCBI登录号
    NP_000601
    UniProt
    P16070
    途径
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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