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SLUG 抗体 (Middle Region)

SNAI2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318763
发货至: 中国
  • 抗原 See all SLUG (SNAI2) 抗体
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 49
    • 17
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 38
    • 11
    克隆类型
    • 39
    • 9
    多克隆
    标记
    • 31
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SLUG antibody is un-conjugated
    应用范围
    • 25
    • 19
    • 12
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects Slug, a member of the Snail family of zinc finger transcription factors, whose expression is induced by FGF, BMP, and TGF-beta. This antibody is not cross-reactive with Snail.
    纯化方法
    Purified
    免疫原
    13 amino acid peptide sequence near the centre of human Slug
    亚型
    IgG
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  • 应用备注
    Western Blot: 0.5 - 2.0g/mL, detects a band of approximately 30 kDa in 293 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for up to one month or at -20 °C for longer. Storage in frost-free freezers is not recommended. This product should be stored undiluted.
  • 抗原
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    别名
    SNAI2 / SLUG (SNAI2 产品)
    背景
    Slug is a 29kD transcriptional repressor, which functions by binding to E-box motifs and inhibiting gene expression by recruiting histone deacetylase-1 (HDAC-1). Slug controls the expression of a wide variety of genes including TP53, BRCA2, PUM and CDH1, and has important roles in apoptosis and epithelial-mesenchymal transition. It is also thought to function in neural crest development. Slug expression in breast, oesophageal, and colorectal carcinomas has been correlated with poor prognosis for survival.Synonyms: Neural crest transcription factor Slug, Protein snail homolog 2, SLUGH, Zinc finger protein SNAI2
    基因ID
    6591
    NCBI登录号
    NP_003059
    UniProt
    O43623
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