Western Blot: 1 - 2g/mL, detects a band of approximately 38 kDa in human lymph nodetissue lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
CD5L is also known as Apoptosis Inhibitor expressed by Macrophages (AIM), and SP alpha. CD5L is a soluble 38kD glycoprotein which is specifically produced by mature macrophages, and has been shown to support their survival and enhance phagocytic function. CD5L expression is upregulated in response to LXR/RXR heterodimer activation. CD5L has been shown to mediate the survival of macrophages in atherosclerotic plaques.Synonyms: SP-ALPHA