Tetanus Toxin 抗体
TetX
适用: Clostridium tetani
WB, EIA
宿主: 山羊
Polyclonal
unconjugated
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- 抗原 See all Tetanus Toxin (TetX) 抗体
- Tetanus Toxin (TetX)
- 适用
- Clostridium tetani
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Tetanus Toxin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects the tetanus toxin which is produced by the soil micro-organism Clostridium tetani. C. tetani infection results in its systemic growth and secretion of tetanus, which causes muscle spasms by inhibiting neurotransmitter release. The antibody also reacts with the C-fragment of tetanus toxin.
- 纯化方法
- Affinity Chromatography.
- 免疫原
- Tetanus Exotoxin
- 亚型
- IgG
- Top Product
- Discover our top product TetX Primary Antibody
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- 应用备注
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ELISA: 1g/mL. Western Blot: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 5.0 mg/mL
- 缓冲液
- PBS pH 7.2 containing 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Tetanus Toxin (TetX)
- 别名
- Tetanus Toxin (TetX 产品)
- 物质类
- Bacteria
- 背景
- Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.Synonyms: Clostridium tetani toxin, tetX
- 基因ID
- 1061100
- NCBI登录号
- NP_783831
- UniProt
- P04958
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