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DNAJB11 抗体

DNAJB11 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317830
发货至: 中国
  • 抗原 See all DNAJB11 抗体
    DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))
    适用
    • 40
    • 18
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    克隆类型
    • 40
    多克隆
    标记
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNAJB11 antibody is un-conjugated
    应用范围
    • 26
    • 22
    • 19
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    ERdj3 antibody detects endogenous levels of ERdj3 protein.(region surrounding Lys66)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product DNAJB11 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))
    别名
    DNAJB11 (DNAJB11 产品)
    别名
    MGC75796 antibody, MGC81924 antibody, ABBP-2 antibody, ABBP2 antibody, DJ9 antibody, Dj-9 antibody, EDJ antibody, ERdj3 antibody, ERj3 antibody, ERj3p antibody, PRO1080 antibody, UNQ537 antibody, hDj-9 antibody, 1810031F23Rik antibody, AL024055 antibody, Dj9 antibody, LRRGT00084 antibody, cb954 antibody, DnaJ heat shock protein family (Hsp40) member B11 antibody, DnaJ heat shock protein family (Hsp40) member B11 S homeolog antibody, DnaJ (Hsp40) homolog, subfamily B, member 11 antibody, dnajb11 antibody, DNAJB11 antibody, dnajb11.S antibody, Dnajb11 antibody
    背景
    Members of the heat shock protein 40 (HSP 40) family of proteins all contain a highly conserved J domain that associates with HSP 70 and regulates the function of HSP 70 by activating its adenosine triphosphatase activity. ERdj3, an HSP 40 chaperone, is expressed in the ER lumen, where it interacts with BiP, a molecule involved in retrotranslocating proteins out of the ER. ERdj3 also associates with several other protein substrates, including unfolded light chains, a nonsecreted Ig light chain mutant and a VSV-G ts045 mutant. Shiga toxin (Stx) is a bacterial tool that enzymatically inactivates the 28S rRNA, inhibiting protein synthesis of infected cells. Stx also interacts with ERdj3 and Sec 61 to form a complex through which proteins are retrotranslocated to the cytoplasm. ERdj3 may play a role in the ER quality control system.Synonyms: APOBEC1-binding protein 2, DnaJ homolog subfamily B member 11, EDJ, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, ER-associated dnaJ protein 3, ERJ3, ERdj3, ERj3p, HEDJ, PSEC0121, PWP1-interacting protein 4, hDj9
    分子量
    approx. 40 kDa
    基因ID
    51726
    NCBI登录号
    NP_057390
    UniProt
    Q9UBS4
    途径
    ER-Nucleus Signaling
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