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HTR5B 抗体

HTR5B 适用: 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317728
发货至: 中国
  • 抗原 See all HTR5B 抗体
    HTR5B (5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B))
    适用
    • 6
    • 5
    • 2
    小鼠, 大鼠
    宿主
    • 7
    克隆类型
    • 7
    多克隆
    标记
    • 7
    This HTR5B antibody is un-conjugated
    应用范围
    • 7
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of SR-5B protein.(region surrounding Val300)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product HTR5B Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HTR5B (5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B))
    别名
    Serotonin Receptor 5B (HTR5B) (HTR5B 产品)
    别名
    5-Ht5b antibody, 5Ht5b antibody, REC17 antibody, 5-hydroxytryptamine (serotonin) receptor 5B antibody, Htr5b antibody
    背景
    SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-1-7 (5-HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.Synonyms: 5-HT-5B, 5-HT5B, 5-hydroxytryptamine receptor 5B, 5HT5B, MR22
    分子量
    approx. 38 kDa
    基因ID
    79247
    NCBI登录号
    XP_001055046
    UniProt
    P35365
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