HTR5B 抗体
Quick Overview for HTR5B 抗体 (ABIN317728)
抗原
See all HTR5B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of SR-5B protein.(region surrounding Val300)
-
纯化方法
- Affinity Chromatography using epitope-specific immunogen
-
-
anti-5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B) (C-Term) antibody
HTR5B 适用: 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B) antibodyHTR5B 适用: 小鼠, 大鼠, 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B) (AA 280-329) antibodyHTR5B 适用: 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B) (C-Term) antibodyHTR5B 适用: 小鼠, 大鼠 WB, ELISA, IF/ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- HTR5B (5-Hydroxytryptamine (serotonin) Receptor 5B (HTR5B))
-
别名
- Serotonin Receptor 5B (HTR5B)
-
背景
- SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-1-7 (5-HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.Synonyms: 5-HT-5B, 5-HT5B, 5-hydroxytryptamine receptor 5B, 5HT5B, MR22
-
分子量
- approx. 38 kDa
-
基因ID
- 79247
-
NCBI登录号
- XP_001055046
-
UniProt
- P35365
抗原
-
