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CCKAR 抗体

CCKAR 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317645
发货至: 中国
  • 抗原 See all CCKAR 抗体
    CCKAR (Cholecystokinin A Receptor (CCKAR))
    适用
    • 59
    • 30
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    • 6
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    人, 大鼠, 小鼠
    宿主
    • 60
    • 2
    • 2
    克隆类型
    • 58
    • 2
    多克隆
    标记
    • 31
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    This CCKAR antibody is un-conjugated
    应用范围
    • 44
    • 18
    • 18
    • 13
    • 13
    • 9
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    • 4
    • 3
    • 2
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of CCK-AR protein.(region surrounding Pro255)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product CCKAR Primary Antibody
  • 应用备注
    ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CCKAR (Cholecystokinin A Receptor (CCKAR))
    别名
    CCK-A Receptor (CCKAR 产品)
    背景
    The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.Synonyms: CCKA Receptor, CCKAR, CCKRA, Cholecystokinin receptor type A, Cholecystokinin-1 receptor
    基因ID
    886
    NCBI登录号
    NP_000721
    UniProt
    P32238
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour
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