CD19 抗体
-
- 抗原 See all CD19 抗体
- CD19 (CD19 Molecule (CD19))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD19 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- This antibody recognises CD19, a 95 kDa cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
- 产品特性
- Synonyms: Leu-12, B-cell marker, Differentiation antigen CD19, B-lymphocyte surface antigen B4
- 纯化方法
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- 免疫原
- Human EB-4 Burkitt lymphoma cell line.
- 克隆位点
- Bu12
- 亚型
- IgG1
- Top Product
- Discover our top product CD19 Primary Antibody
-
-
- 应用备注
-
Flow Cytometry: 1/50 - 1/200, 10l of the suggested working dilution to label 1x10^6 cellsin 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0mg/mL
- 缓冲液
- Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only. - 有效期
- 12 months
-
- 抗原
- CD19 (CD19 Molecule (CD19))
- 别名
- CD19 (CD19 产品)
- 别名
- B4 antibody, CVID3 antibody, AW495831 antibody, CD19 antibody, CD19 molecule antibody, CD19 antigen antibody, CD19 antibody, Cd19 antibody
- 背景
- CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 Molecule is expressed on 100 % of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10 % of normal human peripheral blood cells and approximately 60 % of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12 % of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
- 基因ID
- 930
- UniProt
- P15391
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
-