NF-kB p65 抗体 (pSer536)
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- 抗原 See all NF-kB p65 (NFkBP65) 抗体
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
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抗原表位
- pSer536
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NF-kB p65 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Detects the p65 (RelA) subunit of nuclear factor kappa-B (NFkB) when phosphorylated at serine 536. NFkB is a heterodimeric DNA binding protein which was originally identified consisting of p65 and p50 (NFkB1) subunits. Research has led to the discovery of other subunits, including p52 (NFkB2), cRel, and RelB. NFkB is ubiquitously expressed, and functions as a second messenger which upon activation leads to the transcription of a number of genes. NFkB is activated by a number of agents, including pro-inflammatory cytokines and bacterial lipopolysaccharide, and is essential for the maturation of T cells and regulation of their survival and activation. Phosphorylation of serine 536 contributes to NFkB transactivation and increases p65 transcription activity.
- 纯化方法
- Purified
- 免疫原
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Synthetic peptide corresponding to residues surrounding serine 536 of human NFkB p65 protein. ( pSer536 ).
Type of Immunogen: Synthetic peptide - 亚型
- IgG
- Top Product
- Discover our top product NFkBP65 Primary Antibody
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- 应用备注
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Approved: ELISA (1:500 - 1:3000), IHC, IHC-P (1:50 - 1:250), WB (1:100 - 1:1000)
Usage: Western Blot: LS-C42658 detects a band of approximately 65kD in the appropriate cell lysate. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.2, 0.01 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
- 别名
- RELA / NFKB p65 (NFkBP65 产品)
- 别名
- C-Rel antibody, NFKB3 antibody, p65 antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel reticuloendotheliosis viral oncogene homolog A (avian) antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, REL antibody, RELA antibody, Rela antibody, Rel antibody, rel antibody, rel.L antibody
- 背景
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Name/Gene ID: RELA
Synonyms: RELA, NF-kappa-B p65delta3, NFKB3, p65, Transcription factor p65 - 基因ID
- 5970
- UniProt
- Q04206
- 途径
- NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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