-
- 抗原 See all SRPRB 抗体
- SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))
-
抗原表位
- AA 246-265
-
适用
- 犬
-
宿主
-
绵羊
-
克隆类型
- 多克隆
-
标记
- This SRPRB antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 小鸡, 犬
- 产品特性
- Signal Recognition Particle Receptor, β subunit,The receptor for Signal Recognition Particle (SRP) is the site on the endoplasmic reticulum that ribosomes translating secreted and integral membrane proteins are initially targeted to. Once the ribosome-SRP complex arrives at the SRP receptor the protein being translated is transferred to the translocation complex (Sec61) in the ER membrane. The SRP receptor is composed of two subunits SRalpha and SRbeta. The SRalpha subunit is a translocation GTPase peripherally bound to the endoplasmic reticulum by its interaction with SRbeta. SRalpha also binds to the GTPase of SRP (SRP54) and these two proteins appear to function as each others GTPase activating proteins (GAPs). Hydrolysis of GTP by SRalpha and SRP54 is thought to be involved in transfer of the nascent protein to the Sec61 complex in the ER. SRalpha has an apparent molecular weight of 72 kDa. SRbeta is a Type I transmembrane protein that spans the membrane once and contains Ras type GTPase domain. The function of the GTPase in SRbeta is unknown. The membrane spanning domain is at the amino-terminus of SRbeta. The GTPase domain encompasses three quarters of the protein and is carboxyl- of the transmembrane region. SRalpha binds to the GTPase domain of SRbeta. Heterodimerization of SRalpha and SRbeta masks the carboxyl-terminal epitope of SRbeta.
- 纯化方法
- Ammonium Sulfate Precipitation
- 免疫原
- Synthetic peptide corresponding to amino acids 246-265 derived from the carboxyl terminal of the canine SRbeta subunit.
- 亚型
- IgG
- Top Product
- Discover our top product SRPRB Primary Antibody
-
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibody
SRPRB 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (Middle Region) antibodySRPRB 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibodySRPRB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 57-271) antibodySRPRB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 58-271) antibodySRPRB 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibodySRPRB 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 58-271) antibodySRPRB 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 56-269) antibodySRPRB 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (C-Term) antibodySRPRB 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 182-231) antibodySRPRB 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, 非洲爪蟾, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Detects SRbeta by Western blot analysis at 15 μg/mL. Antibody will not detect SRbeta protein bound to SRalpha. Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
-
- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
-
- 抗原
- SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))
- 别名
- SR beta (SRPRB 产品)
- 别名
- wu:fk57h10 antibody, zgc:111820 antibody, zgc:92746 antibody, apmcf1 antibody, APMCF1 antibody, AA409543 antibody, Ab2-417 antibody, Ba1-667 antibody, Cc1-8 antibody, signal recognition particle receptor, B subunit antibody, SRP receptor beta subunit S homeolog antibody, SRP receptor beta subunit antibody, SRPRB antibody, srprb antibody, srprb.S antibody, Srprb antibody
- 途径
- ER-Nucleus Signaling
-
You are here:
