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HNRNPK 抗体 (C-Term)

HNRNPK 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal F45 P9 C7 unconjugated
产品编号 ABIN307124
发货至: 中国
  • 抗原 See all HNRNPK 抗体
    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
    抗原表位
    • 15
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    C-Term
    适用
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    宿主
    • 77
    • 7
    小鼠
    克隆类型
    • 69
    • 15
    单克隆
    标记
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    This HNRNPK antibody is un-conjugated
    应用范围
    • 62
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    • 14
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    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    小鸡, 人, 小鼠, 兔, 大鼠
    产品特性
    hnRNP-K, CSBP, TUNP, dC-Stretch Binding Protein,Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA Polymerase II. There are approximately 20 known hnRNP proteins, which range in size from 34 kDa to 120 kDa, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K, a 65 kDa protein, recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
    纯化方法
    Protein A/G Chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminal of the hnRNP-K protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse, rat, rabbit and chicken
    克隆位点
    F45 P9 C7
    亚型
    IgG1
    Top Product
    Discover our top product HNRNPK Primary Antibody
  • 应用备注
    Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
    别名
    Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK 产品)
    别名
    CSBP antibody, HNRPK antibody, TUNP antibody, Csbp antibody, Hnrpk antibody, hnrpk antibody, MGC75642 antibody, wu:fb37h02 antibody, wu:fi34c04 antibody, zgc:66162 antibody, KBBP antibody, NOVA antibody, heterogeneous nuclear ribonucleoprotein K antibody, heterogeneous nuclear ribonucleoprotein K S homeolog antibody, heterogeneous nuclear ribonucleoprotein k antibody, HNRNPK antibody, Hnrnpk antibody, hnrnpk.S antibody, hnrnpk antibody, LOC5565718 antibody, CpipJ_CPIJ000130 antibody, NGK_p0004 antibody
    UniProt
    P61978
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