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CSAG2 抗体

CSAG2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN307032
发货至: 中国
  • 抗原 See all CSAG2 抗体
    CSAG2 (CSAG Family, Member 2 (CSAG2))
    适用
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This CSAG2 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 12
    • 2
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    产品特性
    Chondrosarcoma-associated protein 2, Taxol-resistant-associated protein 3, TRAG-3, CSAG2, TRAG3,The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.
    纯化方法
    Ammonium Sulfate Precipitation
    免疫原
    Synthetic peptide derived from the human Trag-3 protein.
    亚型
    IgG
  • 应用备注
    Antibody can be used for Western blotting (0.5-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    CSAG2 (CSAG Family, Member 2 (CSAG2))
    别名
    Trag 3 (Taxol-resistant-associated protein 3) (CSAG2 产品)
    别名
    CSAG1 antibody, CSAG3B antibody, CSAG3 antibody, CT24.2 antibody, TRAG-3 antibody, TRAG3 antibody, chondrosarcoma-associated gene 2/3 protein antibody, CSAG family member 2 antibody, LOC705860 antibody, LOC738247 antibody, CSAG2 antibody
    UniProt
    Q9Y5P2
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