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NPDC1 抗体

NPDC1 适用: 人 WB 宿主: 小鼠 Monoclonal 16E4 unconjugated
产品编号 ABIN306963
发货至: 中国
  • 抗原 See all NPDC1 抗体
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    适用
    • 29
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    宿主
    • 33
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    小鼠
    克隆类型
    • 34
    • 1
    单克隆
    标记
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    This NPDC1 antibody is un-conjugated
    应用范围
    • 26
    • 13
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    • 11
    • 4
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    Western Blotting (WB)
    特异性
    Monoclonal Anti-NPDC-1 (mouse IgG1 isotype) is derived from the hybridoma 16E4 produced by immunizing mice with the peptide SLGSPVSSDPVHMS (Gene ID: 56654).
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptional events mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.
    纯化方法
    Ion-exchange chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with a synthetic peptide SLGSPVSSDPVHMS derived from human NPDC-1 protein (Gene ID: 56654) and mouse myeloma cells.
    克隆位点
    16E4
    亚型
    IgG1
    Top Product
    Discover our top product NPDC1 Primary Antibody
  • 应用备注
    Antibody can be used for Western blotting (1:1000 dilution). Optimal concentration should be evaluated by serial dilutions. Monoclonal Anti-NPDC-1 recognizes human NPDC-1 by immunoblotting (34-40 kDa).
    限制
    仅限研究用
  • 缓冲液
    20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    别名
    NPDC-1 (NPDC1 产品)
    别名
    AI314472 antibody, NPDC-1 antibody, CAB antibody, CAB- antibody, CAB-1 antibody, CAB1 antibody, neural proliferation, differentiation and control, 1, gene 1 L homeolog antibody, neural proliferation, differentiation and control 1 antibody, neural proliferation, differentiation and control, 1 antibody, npdc1.1.L antibody, Npdc1 antibody, NPDC1 antibody
    UniProt
    Q8WXX4
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