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TYROBP 抗体 (Cytoplasmic Domain)

TYROBP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN306916
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    抗原表位
    • 16
    • 15
    • 15
    • 11
    • 1
    • 1
    • 1
    Cytoplasmic Domain
    适用
    • 52
    • 20
    • 4
    宿主
    • 69
    • 1
    • 1
    克隆类型
    • 62
    • 9
    多克隆
    标记
    • 19
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    This TYROBP antibody is un-conjugated
    应用范围
    • 40
    • 30
    • 26
    • 26
    • 20
    • 17
    • 12
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    交叉反应
    人, 小鼠
    产品特性
    TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12, Killer-activating receptor-associated protein, KARAP, TYROBP,DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells (1,2). DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction (3). Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice (4,5), as well as presenile dementia and bone cysts in humans (6).
    纯化方法
    Ammonium Sulfate Precipitation
    免疫原
    Rabbit immunized with recombinant DAP12 protein (cytoplasmic domain).
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    Antibody can be used for immunoprecipitation (2-4 μg/mg of protein lysate). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    DAP12 (TYROBP 产品)
    别名
    TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
    UniProt
    O43914
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