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AKAP12 抗体

AKAP12 适用: 大鼠 WB 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN306674
发货至: 中国
  • 抗原 See all AKAP12 抗体
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    适用
    • 20
    • 4
    • 3
    • 2
    大鼠
    宿主
    • 19
    • 2
    • 2
    • 1
    绵羊
    克隆类型
    • 23
    • 1
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKAP12 antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    亚型
    IgG
    Top Product
    Discover our top product AKAP12 Primary Antibody
  • 应用备注
    Antibody can be used for Western blot (2-5 ug/ml), immunohistochemistry and immunoprecipitation. Positive Control: Rat aortic smooth muscle.
    限制
    仅限研究用
  • 浓度
    1 mg/ml
    储存条件
    -20 °C
  • 抗原
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    别名
    SSeCKS - myristylated (PKC) substrate (AKAP12 产品)
    背景
    Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicatedduring the process of spermiogenesis and in the actin-based stellate morphology of mesangial cellsSynonyms: SSeCKS, A-kinase anchor protein 12, AKAP12, src-suppressed C kinase substrate.
    UniProt
    Q62766
    途径
    cAMP Metabolic Process
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