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Calcineurin A 抗体 (AA 1-205)

CAN 适用: 人 IHC (fro), IHC (p) 宿主: 小鼠, 兔 Monoclonal unconjugated
产品编号 ABIN306658
发货至: 中国
  • 抗原 See all Calcineurin A (CAN) 抗体
    Calcineurin A (CAN)
    抗原表位
    • 10
    • 1
    • 1
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    • 1
    AA 1-205
    适用
    • 25
    • 12
    • 12
    • 2
    • 1
    • 1
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    • 1
    • 1
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    宿主
    • 24
    • 1
    • 1
    小鼠, 兔
    克隆类型
    • 18
    • 8
    单克隆
    标记
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Calcineurin A antibody is un-conjugated
    应用范围
    • 16
    • 12
    • 10
    • 10
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应 (详细)
    Human
    产品特性
    pp2Ba, rabbit anti protein phosphatase 2 B alpha calcineurin, protein phosphatase 3,The combination of AMACR and p63 may be extremely useful for diagnosing PIN and small focus adenocarcinoma, especially in difficult cases and cases with limited tissues. This antibody cocktail may eliminate the need for 34bE12. AMACR stains cytoplasm in prostate adenocarcinoma and PIN while p63 stains basal cell nuclei in PIN and benign prostate glands. P504S (AMACR, Alpha-methylacyl-CoA racemase) is an essential enzyme in the b-oxidation of branched-chain fatty acids. High expression of AMACR protein is found in prostate adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded tissue. The expression of AMACR is also detected in prostate premalignant lesions, such as prostate intraepithelial neoplasia (PIN). The p63 protein, a homologue of the tumor-suppressor p53, is highly expressed in the basal or progenitor layer of many epithelial tissues. p63 is detected in prostate basal cells in normal prostate glands and PIN. However, it is negative in prostate adenocarcinoma. Thus p63 is useful as a differential marker for benign prostate glands and adenocarcinoma (negative marker). Human AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase and human p63 nuclear protein.
    纯化方法
    Affinity purified antibodies
    免疫原
    1. Human recombinant AMACR (P504S) protein, whole sequence (for rabbit monoclonal antibody 13H4), 2. Recombinant human p63 protein aa 1-205 (for mouse monoclonal antibody 4A4)
    亚型
    IgG
    Top Product
    Discover our top product CAN Primary Antibody
  • 应用备注
    Use formalin-fixed and paraffin-embedded sections, Retrieval conditions: Unmasking fluid T, TEC buffer (Tris/EDTA/Citrate) pH 8 in a pressure cooker at 100 °C 20-40 minutes,IHC(C, P),60 min at RT,(RTU) neat
    限制
    仅限研究用
  • 缓冲液
    Affinity purified antibodies in PBS, BSA, sodium azide (0.09 % ). Use antibody dilution buffer containing sufficient protein and preservative.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C
  • 抗原
    Calcineurin A (CAN)
    别名
    Protein Phosphatase 2 B alpha (calcineurin) (CAN 产品)
    别名
    Cna antibody, DDBDRAFT_0185021 antibody, DDBDRAFT_0217855 antibody, DDB_0185021 antibody, DDB_0217855 antibody, PPP3CC antibody, CAN A1/PP2B antibody, CG1455 antibody, CNA1 antibody, Can antibody, Cana1 antibody, CnA antibody, CnnA21EF antibody, D14 antibody, DmCanA1-100B antibody, Dmel\\CG1455 antibody, PP2B antibody, PP2B 21EF antibody, PpD14 antibody, canA antibody, pMY4 antibody, calcineurin A antibody, Calcineurin A antibody, CaM-dependent protein phosphatase, catalytic subunit antibody, protein phosphatase 3 catalytic subunit alpha antibody, Calcineurin A1 antibody, protein phosphatase 3 catalytic subunit beta antibody, Cna antibody, NFIA_077970 antibody, ACLA_011200 antibody, PAS_chr3_0414 antibody, canA antibody, PPP3CA antibody, CanA1 antibody, PPP3CB antibody
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