PPP2R5C 抗体 (AA 53-66)
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Quick Overview for PPP2R5C 抗体 (AA 53-66) (ABIN306656)
抗原
See all PPP2R5C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-66
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原理
- Rabbit anti Human Protein Phosphatase 2 A/B gamma
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产品特性
- Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the , and isoforms. The PP2A/B isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/B is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Antibody raised against synthetic peptide corresponding to amino acids 53 to 66 of the mammalian protein phosphatase 2 A/B conjugated to KLH.
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亚型
- IgG
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应用备注
- Detects PP2A/B isoforms by Western blot analysis. Detects a 56 kDa band in whole rat brain homogenates. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- PPP2R5C (Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2R5C))
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别名
- Protein Phosphatase 2 A/B gamma
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背景
- Protein Phosphatase 2 A/Bγ2
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UniProt
- Q13362, P97888, Q8BG02
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途径
- PI3K-Akt Signaling
抗原
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