(1 reference)-
- 抗原 See all HMMR 抗体
- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
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抗原表位
- AA 706-724, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMMR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Hyaluronan mediated motility receptor(HMMR) detection. Tested with WB, IHC-P in Human.
- 序列
- KEGNTNCYRA PMECQESWK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Hyaluronan mediated motility receptor(HMMR) detection. Tested with WB, IHC-P in Human.
Gene Name: hyaluronan-mediated motility receptor(RHAMM)
Protein Name: Hyaluronan mediated motility receptor - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CD168(706-724aa KEGNTNCYRAPMECQESWK).
- 亚型
- IgG
- Top Product
- Discover our top product HMMR Primary Antibody
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anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 341-440) antibody
HMMR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 306-497) antibodyHMMR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F2C9 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 51-150) antibodyHMMR 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 280-340) antibodyHMMR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 577-724) antibodyHMMR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 1-300) antibodyHMMR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 668-697), (C-Term) antibodyHMMR 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17647 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 478-653) antibodyHMMR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 675-705), (C-Term) antibodyHMMR 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyHMMR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "RHAMM Expression in the Rat Endometrium during the Estrous Cycle and following Implantation." in: Journal of reproduction & infertility, Vol. 13, Issue 3, pp. 131-7, (2013) (PubMed).
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: "RHAMM Expression in the Rat Endometrium during the Estrous Cycle and following Implantation." in: Journal of reproduction & infertility, Vol. 13, Issue 3, pp. 131-7, (2013) (PubMed).
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- 抗原
- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
- 别名
- HMMR (HMMR 产品)
- 别名
- AA386826 antibody, CD168 antibody, Rhamm antibody, RHAMM antibody, IHABP antibody, hyaluronan mediated motility receptor (RHAMM) antibody, hyaluronan-mediated motility receptor antibody, hyaluronan mediated motility receptor antibody, Hmmr antibody, HMMR antibody
- 背景
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HMMR, Hyaluronan-mediated motility receptor, is a protein which in humans is encoded by the HMMR gene. RHAMM was originally discovered as a soluble protein that altered migratory cell behavior and bound to hyaluronan, HMMR is less well studied than the main hyaluronan(HA) receptor, CD44. In contrast to CD44 and other cell-surface receptors which contain the classical membrane spanning domain and signal sequence for secretion from the endoplasmic reticulum/Golgi complex, HMMR does not contain a membrane spanning domain nor does the mRNA transcript contain a signal sequence. HMMR normally is localized inside the cell and is only release by certain, poorly defined stimuli. The transport of HMMR to the extracellular space still is unclear but may involve transport channels or proteins, flippase activity, or exocytosis. Intracellularly, HMMR associates with microtubules and, working with BRCA1 and BARD1, plays a role in the regulation of mitosis. Extracellularly, HMMR associates with CD44, and upon binding to HA, activates intracellular signaling pathways. Variants of HMMR caused by alternative splicing have been observed, but not thoroughly studied.
Synonyms: CD168 antibody|CD168 antigen antibody|HMMR antibody|HMMR_HUMAN antibody|Hyaluronan mediated motility receptor antibody|Hyaluronan-mediated motility receptor(RHAMM) antibody|IHABP antibody|Intracellular hyaluronic acid-binding protein antibody|MGC119494 antibody|MGC119495 antibody|OTTHUMP00000196920 antibody|Receptor for hyaluronan-mediated motility antibody|RHAMM antibody - UniProt
- O75330
- 途径
- Glycosaminoglycan Metabolic Process
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