PMVK 抗体 (Middle Region)
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- 抗原 See all PMVK 抗体
- PMVK (Phosphomevalonate Kinase (PMVK))
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抗原表位
- AA 135-151, Middle Region
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PMVK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Phosphomevalonate kinase(PMVK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- EQSRQQRGWV FTPGVDD
- 交叉反应 (详细)
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Predicted Cross Reactivity: human, mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Phosphomevalonate kinase(PMVK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: phosphomevalonate kinase
Protein Name: Phosphomevalonate kinase(PMKase/hPMK) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PMVK(135-151aa EQSRQQRGWVFTPGVDD), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product PMVK Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- PMVK (Phosphomevalonate Kinase (PMVK))
- 别名
- PMVK (PMVK 产品)
- 别名
- MPK_Bm antibody, F5M6.9 antibody, F5M6_9 antibody, zgc:162701 antibody, HUMPMKI antibody, PMK antibody, PMKA antibody, PMKASE antibody, 1110011E12Rik antibody, 2900002L22Rik antibody, AV001327 antibody, phosphomevalonate kinase antibody, GHMP kinase family protein antibody, PMVK antibody, Mpk antibody, AT1G31910 antibody, CpipJ_CPIJ015413 antibody, Bm1_05275 antibody, pmvk antibody, LOAG_11811 antibody, Tsp_06629 antibody, LOC100282968 antibody, Pmvk antibody
- 背景
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PMVK(phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence(PTS-1), Ser-Arg-Leu, at the C terminus of the protein.
Synonyms: hPMK antibody|HUMPMKI antibody|OTTHUMP00000035546 antibody|Phosphomevalonate kinase antibody|PMK antibody|PMK PEN antibody|PMKA antibody|PMKase antibody|PMKI antibody|PMKPEN antibody|PMVK antibody|PMVK_HUMAN antibody - UniProt
- Q15126
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