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CD40 Ligand 抗体 (N-Term)

Name: CD40 Ligand 抗体 (N-Term)
SKU: ABIN3044319
Availability: OutOfStock

CD40LG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti- CD40Lantibody, Western blotting All lanes: Anti CD40L at 0. (CD40 Ligand 抗体 (N-Term))

Anti CD40Lantibody, IHC(P) IHC(P): Rat Intestine Tissue (CD40 Ligand 抗体 (N-Term))

IHC

Western blot analysis of sCD40L using anti- sCD40L antibody . (CD40 Ligand 抗体 (N-Term))

IHC analysis of sCD40L using anti- sCD40L antibody . (CD40 Ligand 抗体 (N-Term))

IHC

4 images

(1 reference)

产品编号 ABIN3044319

发货至: 中国

Datasheet as PDF

抗原 See all CD40 Ligand (CD40LG) 抗体

CD40 Ligand (CD40LG)
抗原表位
16

9

8

7

6

4

4

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 47-65, N-Term
适用
152

81

34

9

8

6

5

2

2

2

2

1

1

1

1

1
人
宿主
96

66

22

15

12

1
兔
Compatible Secondaries
克隆类型
113

93

4
多克隆
标记
105

23

21

14

8

3

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 Ligand antibody is un-conjugated
应用范围
110

100

53

51

39

29

20

16

15

14

13

13

5

4

4

4

3

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for CD40 ligand(CD40LG) detection. Tested with WB, IHC-P in Human.

序列

HRRLDKIEDE RNLHEDFVF

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for CD40 ligand(CD40LG) detection. Tested with WB, IHC-P in Human.
Gene Name: CD40 ligand
Protein Name: CD40 ligand(CD40-L)

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human CD40L(47-65aa HRRLDKIEDERNLHEDFVF), different from the related mouse sequence by three amino acids, rat sequence by four amino acids.

亚型

IgG

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anti-CD40 Ligand (CD40LG) (AA 1-261) antibody
CD40LG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 108-261) antibody
CD40LG 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal CD40LG-2763 unconjugated

anti-CD40 Ligand (CD40LG) (AA 108-261) antibody
CD40LG 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal CD40LG-2761 unconjugated

anti-CD40 Ligand (CD40LG) antibody (FITC)
CD40LG 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal MR-1 FITC

anti-CD40 Ligand (CD40LG) (AA 79-129) antibody
CD40LG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 33-62) antibody
CD40LG 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 111-261) antibody
CD40LG 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) antibody (PE)
CD40LG 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 24-31 PE

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8H10F5 unconjugated

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5A3A9 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Yang, Fang, Liu, Zhang, Shi, Ji, Lin, Lin: "Protective effects of chinese traditional medicine buyang huanwu decoction on myocardial injury." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2011, pp. 930324, (2012) (PubMed).
抗原

CD40 Ligand (CD40LG)

别名

CD40LG (CD40LG 产品)

别名

CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody

背景

CD40 ligand(CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells. CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions.

Synonyms: CD 154 antibody|CD 40L antibody|CD154 antibody|CD154 antigen antibody|CD40 antigen ligand antibody|CD40 homologue antibody|CD40 L antibody|CD40 ligand antibody|CD40 ligand, soluble form antibody|CD40-L antibody|CD40L_HUMAN antibody|CD40LG antibody|gp39 antibody|hCD40L antibody|HIGM1 antibody|Hyper IgM syndrome antibody|IGM antibody|IMD3 antibody|Ly62 antibody|T B cell activating molecule antibody|T BAM antibody|T cell antigen GP39 antibody|T-cell antigen Gp39 antibody|TBAM antibody|TNF related activation protein antibody|TNF superfamily member 5 antibody|TNF-related activation protein antibody|Tnfsf5 antibody|TRAP antibody|Tumor Necrosis Factor(ligand) Superfamily Member 5 antibody|Tumor necrosis factor ligand superfamily member 5 antibody

UniProt

P29965

途径

NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints