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IL-4 抗体 (Middle Region)

Name: IL-4 抗体 (Middle Region)
SKU: ABIN3044141
Availability: OutOfStock

IL4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Interleukin 4 (IL4) (AA 72-88), (Middle Region) antibody (ABIN3044141) (IL-4 抗体 (Middle Region))

Anti-IL4 antibody, IHC(P) IHC(P): Human Tonsil Tissue (IL-4 抗体 (Middle Region))

IHC

2 images

(4 references)

产品编号 ABIN3044141

发货至: 中国

Datasheet as PDF

抗原 See all IL-4 (IL4) 抗体

IL-4 (IL4) (Interleukin 4 (IL4))
抗原表位
18

11

6

6

5

5

5

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 72-88, Middle Region
适用
141

59

24

14

12

10

10

8

7

5

5

4

3

3

3

3

2

2

1
人
宿主
116

63

55

7

3

2
兔
Compatible Secondaries
克隆类型
126

117

1
多克隆
标记
139

35

17

14

14

9

2

2

2

2

2

2

2

1

1

1

1

1
This IL-4 antibody is un-conjugated
应用范围
128

121

72

62

25

21

19

13

13

13

13

12

9

9

7

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Interleukin-4(IL4) detection. Tested with WB, IHC-P in Human.

序列

AATVLRQFYS HHEKDTR

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Interleukin-4(IL4) detection. Tested with WB, IHC-P in Human.
Gene Name: interleukin 4
Protein Name: Interleukin-4(IL-4)

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human IL-4(72-88aa, AATVLRQFYSHHEKDTR).

亚型

IgG

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应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
Presti, DOrazio, Labra, La Ferla, Mezzasalma, Bizzaro, Giardina, Michelotti, Tursi, Vassallo, Di Gennaro: "Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect." in: Applied microbiology and biotechnology, Vol. 99, Issue 13, pp. 5613-26, (2015) (PubMed).

Yan, Wang, Liang, Fu, Guo: "HPV16L1-attenuated Shigella recombinant vaccine induced strong vaginal and systemic immune responses in guinea pig model." in: Human vaccines & immunotherapeutics, Vol. 10, Issue 12, pp. 3491-8, (2015) (PubMed).

Wang, Feng, Shi, Hao, Yang, Zhang, Kong: "Silencing of miR155 promotes the production of inflammatory mediators in Guillain-Barré syndrome in vitro." in: Inflammation, Vol. 36, Issue 2, pp. 337-45, (2013) (PubMed).

Tan, Liu, Yang, Wang, Qin: "An inactivated Pseudomonas aeruginosa medicament inhibits airway allergic inflammation and improves epithelial functions." in: The journal of physiological sciences : JPS, Vol. 63, Issue 1, pp. 63-9, (2012) (PubMed).
抗原

IL-4 (IL4) (Interleukin 4 (IL4))

别名

IL4 (IL4 产品)

别名

IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody

背景

Interleukin-4(IL-4), also knowns as a B-cell stimulatory factor1(BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells. The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5. The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.

Synonyms: B cell growth factor 1 antibody|B cell IgG differentiation factor antibody|B Cell Stimulatory Factor 1 antibody|B-cell stimulatory factor 1 antibody|BCGF 1 antibody|BCGF1 antibody|Binetrakin antibody|BSF 1 antibody|BSF-1 antibody|BSF1 antibody|HCGF antibody|Hodgkin's Cell Growth Factor antibody|IA Inducing Factor antibody|IGG1 induction factor antibody|IL 4 antibody|IL-4 antibody|IL4 antibody|IL4_HUMAN antibody|Il4e12 antibody|Interleukin 4 antibody|Interleukin 4, isoform 1 antibody|Interleukin-4 antibody|Interleukin4 antibody|Lymphocyte stimulatory factor 1 antibody|Macrophage fusion factor antibody|Mast cell growth factor 2 antibody|MCGF2 antibody|MFF antibody|MGC79402 antibody|Pitrakinra antibody|T cell growth factor 2 antibody|TCGF2 antibody

UniProt

P05112

途径

JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation