NOX1 抗体 (Middle Region)
(3 references)-
- 抗原 See all NOX1 抗体
- NOX1 (NADPH Oxidase 1 (NOX1))
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抗原表位
- AA 354-374, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for NADPH oxidase 1(NOX1) detection. Tested with WB, IHC-P in Human.
- 序列
- HIRAAGDWTE NLIRAFEQQY S
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for NADPH oxidase 1(NOX1) detection. Tested with WB, IHC-P in Human.
Gene Name: NADPH oxidase 1
Protein Name: NADPH oxidase 1(NOX-1) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human NOX1(354-374aa, HIRAAGDWTENLIRAFEQQYS).
- 亚型
- IgG
- Top Product
- Discover our top product NOX1 Primary Antibody
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anti-NADPH Oxidase 1 (NOX1) antibody
NOX1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 235-488) antibodyNOX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (C-Term) antibodyNOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (Internal Region) antibodyVerified NOX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (C-Term) antibodyNOX1 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 斑马鱼, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 291-544) antibodyNOX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 418-564) antibodyNOX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 425-515) antibodyNOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 200-300) antibodyNOX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 417-431), (Middle Region) antibodyNOX1 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis." in: Antioxidants & redox signaling, (2018) (PubMed).
: "Cordyceps sinensis polysaccharide inhibits PDGF-BB-induced inflammation and ROS production in human mesangial cells." in: Carbohydrate polymers, Vol. 125, pp. 135-45, (2015) (PubMed).
: "Regulation of transforming growth factor beta 1 gene expression by dihydropteridine reductase in kidney 293T cells." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 91, Issue 3, pp. 187-93, (2013) (PubMed).
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: "A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis." in: Antioxidants & redox signaling, (2018) (PubMed).
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- 抗原
- NOX1 (NADPH Oxidase 1 (NOX1))
- 别名
- NOX1 (NOX1 产品)
- 别名
- GP91-2 antibody, MOX1 antibody, NOH-1 antibody, NOH1 antibody, NOX1a antibody, NOX1alpha antibody, Nox-1 antibody, Nox1 antibody, NADPH oxidase 1 antibody, NOX1 antibody, Nox1 antibody, nox1 antibody
- 背景
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NOX1(NADPH OXIDASE 1), also known as NOH1, MOX1 or GP91-2, is an enzyme that in humans is encoded by the NOX1 gene. It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. The NOX1 gene is mapped to Xq22.1. NOX1 was expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes. The deduced 564-amino acid NOX1 protein, which is 58 % identical to CYBB, contains 6 membrane-spanning regions, conserved flavin and pyridine nucleotide-binding sites, and histidines possibly involved in heme ligation. Overexpression of MOX1 in NIH 3T3 cells increased superoxide generation and cell growth. Cells expressing MOX1 had a transformed appearance, showed anchorage-independent growth, and produced tumors in athymic mice. Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice. However, 50 % survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion.
Synonyms: GP91 2 antibody|Mitogenic oxidase(pyridine nucleotide dependent superoxide generating) antibody|Mitogenic oxidase 1 antibody|MOX-1 antibody|MOX1 antibody|NADH/NADPH mitogenic oxidase subunit P65 MOX antibody|NADH/NADPH mitogenic oxidase subunit P65-MOX antibody|NADPH oxidase 1 antibody|NADPH oxidase 1 variant NOH 1L antibody|NADPH oxidase homolog 1 antibody|NOH 1 antibody|NOH-1 antibody|NOH1 antibody|NOX-1 antibody|Nox1 antibody|NOX1_HUMAN antibody|RP1 146H21.1 antibody - UniProt
- Q9Y5S8
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
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