RGS3 抗体 (C-Term)
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- 抗原 See all RGS3 抗体
- RGS3 (Regulator of G-Protein Signaling 3 (RGS3))
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抗原表位
- AA 909-925, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RGS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Regulator of G-protein signaling 3(Rgs3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- DSYTREHTKE NLQSITR
- 交叉反应 (详细)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Regulator of G-protein signaling 3(Rgs3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: regulator of G-protein signaling 3
Protein Name: Regulator of G-protein signaling 3 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse RGS3(909-925aa DSYTREHTKENLQSITR), identical to the related rat sequence, and different from the related human sequence by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RGS3 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- RGS3 (Regulator of G-Protein Signaling 3 (RGS3))
- 别名
- Rgs3 (RGS3 产品)
- 别名
- RGS3 antibody, MGC115680 antibody, C2PA antibody, RGP3 antibody, 4930506N09Rik antibody, C2PA-RGS3 antibody, C2pa antibody, PDZ-RGS3 antibody, RGS3S antibody, SRB-RGS antibody, regulator of G protein signaling 3 antibody, regulator of G-protein signaling 3 L homeolog antibody, regulator of G-protein signaling 3 antibody, RGS3 antibody, rgs3.L antibody, Rgs3 antibody
- 背景
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RGS3(Regulator of G Protein Signaling 3), is a protein that in humans is encoded by the RGS3 gene. Chatterjee et al.(1997) studied RGS3, the largest member of the RGS family then identified. Mouse Pdz-Rgs3 can mediate signaling from the ephrin-B cytoplasmic tail. By radiation hybrid mapping, Chatterjee et al.(1997) assigned the RGS3 gene to chromosome 9q31-q33. Lu et al.(2001) showed that Sdf1, a chemokine with a G protein-coupled receptor, and Bdnf are chemoattractants for cerebellar granule cells, and that Sdf1 chemoattraction is selectively inhibited by soluble ephrin-B receptor. This inhibition could be blocked by a truncated Pdz-Rgs3 protein lacking the RGS domain.
Synonyms: C2PA antibody|FLJ20370 antibody|FLJ31516 antibody|FLJ90496 antibody|PDZ RGS 3 antibody|PDZ RGS3 antibody|Regulator of G protein signaling 3 antibody|Regulator of G protein signalling 3 antibody|Regulator of G-protein signaling 3 antibody|RGP 3 antibody|RGP3 antibody|RGS 3 antibody|RGS3 antibody|RGS3_HUMAN antibody - 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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