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- 抗原 See all CUEDC2 抗体
- CUEDC2 (CUE Domain Containing 2 (CUEDC2))
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抗原表位
- AA 267-287, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CUEDC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for CUE domain-containing protein 2(CUEDC2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- EAEEMKATYI NLKPARKYRF H
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for CUE domain-containing protein 2(CUEDC2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: CUE domain containing 2
Protein Name: CUE domain-containing protein 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CUEDC2(267-287aa EAEEMKATYINLKPARKYRFH), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product CUEDC2 Primary Antibody
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anti-CUE Domain Containing 2 (CUEDC2) (AA 201-287) antibody
CUEDC2 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) antibodyCUEDC2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (AA 1-226) antibodyCUEDC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (C-Term) antibodyCUEDC2 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (AA 239-267), (C-Term) antibodyCUEDC2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19592 unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (AA 250-300) antibodyCUEDC2 适用: 人, 小鼠, 马, Cow, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (AA 50-100) antibodyCUEDC2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (AA 239-267) antibodyCUEDC2 适用: 人 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (AA 1-150) antibodyCUEDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CUE Domain Containing 2 (CUEDC2) (C-Term) antibodyCUEDC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for CUEDC2 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- CUEDC2 (CUE Domain Containing 2 (CUEDC2))
- 别名
- CUEDC2 (CUEDC2 产品)
- 别名
- cuedc2 antibody, MGC81368 antibody, C10orf66 antibody, bA18I14.5 antibody, 3010002G01Rik antibody, wu:fi42e02 antibody, zgc:92255 antibody, CUE domain containing 2 S homeolog antibody, CUE domain containing 2 antibody, CUE domain containing 2 L homeolog antibody, cuedc2.S antibody, CUEDC2 antibody, cuedc2.L antibody, cuedc2 antibody, Cuedc2 antibody
- 背景
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CUEDC2(Cue Domain-Containing Protein 2) is involved in ubiquitin-and proteasome-mediated degradation of progesterone receptor(PR, or PGR) and estrogen receptor(ER)-alpha. Hartz(2011) mapped the CUEDC2 gene to chromosome 10q24.32 based on an alignment of the CUEDC2 sequence with the genomic sequence(GRCh37). Using coimmunoprecipitation analysis and protein pull-down assays, Zhang et al.(2007) confirmed that CUEDC2 interacted with the PRB isoform of PR. Mutation analysis revealed that the IF domain of PRB and the CUE domain of CUEDC2 were required for the interaction. CUEDC2 reduced PRB protein content and promoted progesterone-induced PRB degradation via the ubiquitin-proteasome pathway.
Synonyms: bA18I14.5 antibody|C10orf66 antibody|Chromosome 10 open reading frame 66 antibody|CUE domain containing 2 antibody|CUE domain-containing protein 2 antibody|CUED2 antibody|CUED2_HUMAN antibody|Cuedc2 antibody|MGC2491 antibody|OTTHUMP00000020368 antibody - UniProt
- Q9H467
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