POR 抗体 (C-Term)
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- 抗原 See all POR 抗体
- POR (P450 (Cytochrome) Oxidoreductase (POR))
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抗原表位
- AA 659-677, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for NADPH--cytochrome P450 reductase(POR) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- DYIKKLMTKG RYSLDVWS
- 交叉反应 (详细)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for NADPH--cytochrome P450 reductase(POR) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: P450(cytochrome) oxidoreductase
Protein Name: NADPH--cytochrome P450 reductase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human POR (659-677aa DYIKKLMTKGRYSLDVWS), different from the related rat and mouse sequences by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product POR Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- POR (P450 (Cytochrome) Oxidoreductase (POR))
- 别名
- POR (POR 产品)
- 别名
- CPR antibody, CYPOR antibody, P450R antibody, POR antibody, CCR antibody, CG11567 antibody, DMR antibody, DmCPR antibody, Dmel\\CG11567 antibody, NCPR antibody, P450 antibody, cpr antibody, zgc:110032 antibody, npr antibody, xpor antibody, 4933424M13Rik antibody, PORCINO antibody, T5J17.90 antibody, T5J17_90 antibody, TFC C antibody, TUBULIN-FOLDING COFACTOR C antibody, cytochrome p450 oxidoreductase antibody, P450 (cytochrome) oxidoreductase antibody, ADP-ribosylation factor interacting protein 2 antibody, Cytochrome P450 reductase antibody, P450 (cytochrome) oxidoreductase a antibody, P450 (cytochrome) oxidoreductase L homeolog antibody, NADPH--cytochrome P450 reductase antibody, C-CAP/cofactor C-like domain-containing protein antibody, POR antibody, Arfip2 antibody, Por antibody, Cpr antibody, pora antibody, por.L antibody, LOC100406157 antibody, por antibody, LOC100619047 antibody
- 背景
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POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Synonyms: CPR antibody|CYPOR antibody|DKFZp686G04235 antibody|FLJ26468 antibody|NADPH Cytochrome P450 Reductase antibody|NADPH dependent cytochrome P450 reductase antibody|NADPH--cytochrome P450 reductase antibody|NCPR_HUMAN antibody|P450(cytochrome) oxidoreductase antibody|P450 Cytochrome Oxidoreductase antibody|P450R antibody|POR antibody - UniProt
- P16435
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
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