EGR1 抗体 (N-Term)
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- 抗原 See all EGR1 抗体
- EGR1 (Early Growth Response 1 (EGR1))
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抗原表位
- AA 23-43, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EGR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 原理
- Rabbit IgG polyclonal antibody for Early growth response protein 1(EGR1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
- 序列
- FPHSPTMDNY PKLEEMMLLS N
- 交叉反应 (详细)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Early growth response protein 1(EGR1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: early growth response 1
Protein Name: Early growth response protein 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Egr1(23-43aa FPHSPTMDNYPKLEEMMLLSN), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product EGR1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).
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ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).
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- 抗原
- EGR1 (Early Growth Response 1 (EGR1))
- 别名
- EGR1 (EGR1 产品)
- 别名
- AT225 antibody, G0S30 antibody, KROX-24 antibody, NGFI-A antibody, TIS8 antibody, ZIF-268 antibody, ZNF225 antibody, A530045N19Rik antibody, ETR103 antibody, Egr-1 antibody, Krox-1 antibody, Krox-24 antibody, Krox24 antibody, NGF1-A antibody, NGFIA antibody, Zenk antibody, Zfp-6 antibody, Zif268 antibody, egr antibody, Ngf1 antibody, Ngfi antibody, zif-268 antibody, EGR1 antibody, EGR-1-A antibody, Xegr-1 antibody, at225 antibody, egr-1 antibody, egr1 antibody, g0s30 antibody, krox-24 antibody, ngfi-a antibody, tis8 antibody, znf225 antibody, krox24 antibody, wu:fj64b05 antibody, wu:fq25f01 antibody, EGR-1 antibody, zenk antibody, EGR-1-B antibody, egr1-a antibody, egr1-b antibody, early growth response 1 antibody, early growth response protein 1 (egr-1) antibody, early growth response 1 L homeolog antibody, early growth response 1 S homeolog antibody, EGR1 antibody, CNK00890 antibody, Egr1 antibody, egr1.L antibody, egr1 antibody, egr1.S antibody
- 背景
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Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.
Synonyms: AT 225 antibody|AT225 antibody|Early growth response 1 antibody|Early growth response protein 1 antibody|EGR 1 antibody|EGR-1 antibody|EGR1 antibody|EGR1_HUMAN antibody|G0S 30 antibody|G0S30 antibody|KROX 24 antibody|Krox 24 protein antibody|KROX24 antibody|Nerve growth factor induced protein A antibody|Nerve growth factor-induced clone A antibody|Nerve growth factor-induced protein A antibody|NGFI A antibody|NGFI-A antibody|NGFIA antibody|TIS 8 antibody|TIS8 antibody|Transcription factor ETR 103 antibody|Transcription factor ETR103 antibody|Transcription factor Zif 268 antibody|Transcription factor Zif268 antibody|Zfp 6 antibody|ZIF 268 antibody|ZIF268 antibody|Zinc finger protein 225 antibody|Zinc finger protein Krox-24 antibody|ZNF 225 antibody|ZNF225 antibody - UniProt
- P18146
- 途径
- Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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