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Prolactin Receptor 抗体 (C-Term)

PRLR 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043973
发货至: 中国
  • 抗原 See all Prolactin Receptor (PRLR) 抗体
    Prolactin Receptor (PRLR)
    抗原表位
    • 15
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    • 2
    • 2
    • 1
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    AA 591-605, C-Term
    适用
    • 76
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    • 23
    • 3
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    • 2
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    人, 大鼠
    宿主
    • 49
    • 31
    • 2
    • 1
    克隆类型
    • 49
    • 33
    • 1
    多克隆
    标记
    • 42
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    This Prolactin Receptor antibody is un-conjugated
    应用范围
    • 49
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Prolactin receptor(PRLR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    QLGRLDYLDP TCFMH
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Prolactin receptor(PRLR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: prolactin receptor
    Protein Name: Prolactin receptor
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse PRLR (591-605aa QLGRLDYLDPTCFMH), identical to the related rat sequence, and different from the related human sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PRLR Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." in: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

  • 抗原
    Prolactin Receptor (PRLR)
    别名
    PRLR (PRLR 产品)
    别名
    hPRLrI antibody, PRL-R antibody, prlr antibody, PRLRb antibody, PRLR antibody, tprlr antibody, DKFZp469D061 antibody, RATPRLR antibody, AI987712 antibody, Pr-1 antibody, Pr-3 antibody, Prlr-rs1 antibody, wu:fj65c07 antibody, prolactin receptor antibody, prolactin receptor L homeolog antibody, prolactin receptor S homeolog antibody, prolactin receptor a antibody, PRLR antibody, prlr.L antibody, prlr.S antibody, PR antibody, prlr antibody, Prlr antibody, prlra antibody
    背景
    PRLR(Prolactin Receptor), is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al.(1989, 1990) demonstrated that the prolactin receptor gene resides in the same chromosomal region as the growth hormone receptor gene, which has been mapped to 5p13-p12. Cunningham et al.(1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to the growth hormone receptor or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues(histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR(conserved in all PRL receptors but not GH receptors) are likely zinc-ion ligands.

    Synonyms: AI987712 antibody|CLONE SPM213 antibody|CPRLP antibody|Delta 4-delta 7/11 truncated prolactin receptor antibody|Delta 4-SF1b truncated prolactin receptor antibody|hPRL receptor antibody|hPRLrI antibody|Lactogen receptor antibody|MGC105486 antibody|OPR antibody|OTTHUMP00000115998 antibody|Pr-1 antibody|Pr-3 antibody|PRL R antibody|PRL-R antibody|PRLR antibody|Prlr-rs1 antibody|PRLR_HUMAN antibody|Prolactin receptor a antibody|Prolactin receptor antibody|Prolactin receptor delta 7/11 antibody|RATPRLR antibody|Secreted prolactin binding protein antibody|Truncated testis-specific box 1-C prolactin receptor antibody|wu:fj65c07 antibody
    UniProt
    Q08501
    途径
    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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