SLC9A1 抗体 (AA 543-815)
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- 抗原 See all SLC9A1 抗体
- SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
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抗原表位
- AA 543-815
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC9A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Sodium/hydrogen exchanger 1(SLC9A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Sodium/hydrogen exchanger 1(SLC9A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
Protein Name: Sodium/hydrogen exchanger 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human SLC9A1 recombinant protein (Position: H543-Q815). Human SLC9A1 shares 92% and 93% amino acid (aa) sequences identity with mouse and rat SLC9A1, respectively.
- 亚型
- IgG
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for SLC9A1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))
- 别名
- SLC9A1 (SLC9A1 产品)
- 别名
- AT-NHX1 antibody, ATNHX antibody, ATNHX1 antibody, NA(+)/H(+) ANTIPORTER antibody, Na+/H+ exchanger 1 antibody, T21B4.60 antibody, T21B4_60 antibody, AW554487 antibody, Apnh antibody, Nhe1 antibody, swe antibody, NHE-1 antibody, NHE1 antibody, APNH antibody, Na+/H+ exchanger 1 antibody, solute carrier family 9 (sodium/hydrogen exchanger), member 1 antibody, solute carrier family 9 member A1 antibody, NHX1 antibody, Slc9a1 antibody, SLC9A1 antibody
- 背景
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NHE1, also known as SLC9A1, is an isoform of sodium-hydrogen antiporter that in humans is encoded by the SLC9A1 gene. It is mapped to 1p36.11. NHE1 is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others. The plasma membrane ion exchanger NHE1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. And a structural role for NHE1 in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. NHE1 is a plausible candidate gene for human essential hypertension.
Synonyms: amiloride-sensitive antibody|APNH antibody|APNH1 antibody|FLJ42224 antibody|Na Li countertransporter antibody|Na(+)/H(+) antiporter antibody|Na(+)/H(+) exchanger 1 antibody|Na+ H+ antiporter amiloride-sensitive antibody|Na+ H+ antiporter antibody|Na+ H+ exchanger 1 antibody|NHE-1 antibody|NHE1 antibody|OTTHUMP00000004468 antibody|SL9A1_HUMAN antibody|SLC9A1 antibody|Sodium hydrogen exchanger 1 antibody|Sodium/hydrogen exchanger 1 antibody|solute carrier family 9 antibody|Solute carrier family 9 member 1 antibody|Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody|Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody|Solute carrier family 9 subfamily A member 1 antibody - 基因ID
- 6548
- UniProt
- P19634
- 途径
- Glycosaminoglycan Metabolic Process, Proton Transport
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