Peroxiredoxin 1 抗体 (Middle Region)
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- 抗原 See all Peroxiredoxin 1 (PRDX1) 抗体
- Peroxiredoxin 1 (PRDX1)
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抗原表位
- AA 100-128, Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Peroxiredoxin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Peroxiredoxin-1(PRDX1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- MNIPLVSDPK RTIAQDYGVL KADEGISFR
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Peroxiredoxin-1(PRDX1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: peroxiredoxin 1
Protein Name: Peroxiredoxin-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Peroxiredoxin 1 (100-128aa MNIPLVSDPKRTIAQDYGVLKADEGISFR), different from the related mouse sequence by one amino acid, and identical to the related rat sequence.
- 亚型
- IgG
- Top Product
- Discover our top product PRDX1 Primary Antibody
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anti-Peroxiredoxin 1 (PRDX1) antibody
KO Validated PRDX1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 1 (PRDX1) antibodyPRDX1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 7A1 unconjugated
anti-Peroxiredoxin 1 (PRDX1) (AA 1-100) antibodyPRDX1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 1 (PRDX1) (AA 1-199) antibodyPRDX1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 1 (PRDX1) antibodyPRDX1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2J5 unconjugated
anti-Peroxiredoxin 1 (PRDX1) (AA 1-199) antibodyPRDX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B11-D10 unconjugated
anti-Peroxiredoxin 1 (PRDX1) (Internal Region) antibodyVerified PRDX1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Peroxiredoxin 1 (PRDX1) (AA 19-116) antibodyPRDX1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 1 (PRDX1) (AA 1-184) antibodyPRDX1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 1 (PRDX1) (AA 88-116) antibodyPRDX1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20885 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Peroxiredoxin 1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Peroxiredoxin 1 (PRDX1)
- 别名
- PRDX1 (PRDX1 产品)
- 别名
- MSP23 antibody, NKEF-A antibody, NKEFA antibody, PAG antibody, PAGA antibody, PAGB antibody, PRX1 antibody, PRXI antibody, TDPX2 antibody, NkefA antibody, OSF-3 antibody, OSF3 antibody, Paga antibody, PrdxI antibody, PrxI antibody, TDX2 antibody, TPxA antibody, Tdpx2 antibody, prx1 antibody, Hbp23 antibody, MGC80194 antibody, MGC84820 antibody, PRDX1 antibody, msp23 antibody, nkefa antibody, pag antibody, paga antibody, pagb antibody, prx-1 antibody, prxi antibody, tdpx2 antibody, hm:zehl0637 antibody, zgc:110343 antibody, TPX-2 antibody, peroxiredoxin 1 antibody, peroxiredoxin 1 S homeolog antibody, peroxiredoxin-1 pseudogene antibody, PRDX1 antibody, Prdx1 antibody, prdx1.S antibody, prdx1 antibody, LOC100350232 antibody
- 背景
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PRDX1(Peroxiredoxin 1), also called PRX1, PAGA or NKEFA, is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone, respectively. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The PRDX1 gene is mapped on 1p34.1. Prdx1 was expressed in differentiating motor neuron cells in developing embryonic chicken and mouse spinal cords. mmunoprecipitation analysis showed that GDE2 interacted directly with PRDX1 in embryonic chicken spinal cord extracts and in transfected HEK293T cells. This protein may have a proliferative effect and play a role in cancer development or progression. In differentiating spinal cord, Prdx1 was required to activate Gde2 by reducing an intramolecular cystine bridge between the Gde2 N- and C-terminal domains. An intramolecular disulfide bond between the GDE2 N- and C-terminal domains inhibits GDE2 function, and that reduction of this cystine by PRDX1 activates GDE2 for the induction of motor neuron differentiation.
Synonyms: Hbp23 antibody|Heme binding 23 kDa protein antibody|Macrophage 23 Kd stress protein antibody|Macrophage 23 kDa stress protein antibody|Macrophase stress protein 22 kDa antibody|Macrophase stress protein 23 kd antibody|MSP23 antibody|Natural killer cell enhancing factor A antibody|Natural killer cell-enhancing factor A antibody|Natural killer enhancing factor A antibody|NKEF A antibody|NKEF-A antibody|NkefA antibody|OSF3 antibody|Osteoblast specific factor 3 antibody|PAG antibody|Paga antibody|PAGB antibody|Peroxiredoxin-1 antibody|Prdx 1 antibody|Prdx1 antibody|PRDX1_HUMAN antibody|Proliferation associated gene A antibody|Proliferation associated protein PAG antibody|Proliferation-associated gene protein antibody|PrxI antibody|Tdpx 2 antibody|Tdpx2 antibody|TDX2 antibody|Thioredoxin dependent peroxide reductase 2 antibody|Thioredoxin peroxidase 2 antibody|Thioredoxin-dependent peroxide reductase 2 antibody|TPxA antibody|Trx dependent peroxide reductase 2 antibody - 基因ID
- 5052
- UniProt
- Q06830
- 途径
- p53 Pathway, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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