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NOD1 抗体 (AA 1-160)

NOD1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043890
发货至: 中国
  • 抗原 See all NOD1 抗体
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    抗原表位
    • 12
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-160
    适用
    • 39
    • 19
    • 11
    人, 大鼠
    宿主
    • 42
    • 3
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOD1 antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Nucleotide-binding oligomerization domain-containing protein 1(NOD1) detection. Tested with WB, IHC-P in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Nucleotide-binding oligomerization domain-containing protein 1(NOD1) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: nucleotide-binding oligomerization domain containing 1
    Protein Name: Nucleotide-binding oligomerization domain-containing protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human CARD4 recombinant protein (Position: M1-M160). Human CARD4 shares 82% amino acid (aa) sequence identity with mouse CARD4.
    亚型
    IgG
    Top Product
    Discover our top product NOD1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for CARD4 is approximately 0.2 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    别名
    NOD1 (NOD1 产品)
    别名
    CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
    背景
    Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.

    Synonyms: CARD 4 antibody|CARD4 antibody|Caspase recruitment domain 4 antibody|Caspase recruitment domain containing protein 4 antibody|Caspase recruitment domain family member 4 antibody|Caspase recruitment domain protein 4 antibody|Caspase recruitment domain-containing protein 4 antibody|CLR 7.1 antibody|CLR7.1 antibody|NLR family CARD domain containing 1 antibody|NLRC 1 antibody|NLRC1 antibody|NOD 1 antibody|Nod1 antibody|NOD1 protein antibody|NOD1_HUMAN antibody|Nucleotide binding oligomerization domain containing 1 antibody|Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1 antibody|Nucleotide-binding oligomerization domain-containing protein 1 antibody|Protein Nod1 antibody
    基因ID
    10392
    UniProt
    Q9Y239
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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