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MMP7 抗体 (AA 95-264)

MMP7 适用: 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043881
发货至: 中国
  • 抗原 See all MMP7 抗体
    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
    抗原表位
    • 16
    • 14
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-264
    适用
    • 71
    • 28
    • 28
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 73
    • 16
    • 1
    克隆类型
    • 76
    • 14
    多克隆
    标记
    • 44
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP7 antibody is un-conjugated
    应用范围
    • 64
    • 36
    • 30
    • 22
    • 13
    • 13
    • 11
    • 10
    • 9
    • 9
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Matrilysin(MMP7) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Matrilysin(MMP7) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.
    Gene Name: matrix metallopeptidase 7 (matrilysin, uterine)
    Protein Name: Matrilysin
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived mouse MMP7 recombinant protein (Position: Y95-L264). Mouse MMP7 shares 71% and 90% amino acid (aa) sequences identity with human and rat MMP7, respectively.
    亚型
    IgG
    Top Product
    Discover our top product MMP7 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for MMP7 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Li, Xiao, Li, Li, Zeng, Liu, Liang, Li, Chu, Yang: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).

    Jia, Jiang, Liu, Wang, Zhu, Zhu, Liu, Zhong, Xie, Huang, Jia, Li, Liu, Zuo, Cheng, Dai, Ren: "Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells." in: International journal of oncology, Vol. 52, Issue 6, pp. 1787-1800, (2018) (PubMed).

    Bai, Luo: "5-Hydroxy-4'-Nitro-7-Propionyloxy-Genistein Inhibited Invasion and Metastasis via Inactivating Wnt/b-Catenin Signal Pathway in Human Endometrial Carcinoma Ji Endometrial Cells." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 3230-3243, (2018) (PubMed).

    Li, Li, Zeng, Liu, Yang: "H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression." in: Renal failure, Vol. 39, Issue 1, pp. 265-272, (2017) (PubMed).

    Gao, Tang, He, Liu, Mao, Ji, Lin, Wu: "Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats." in: Frontiers in pharmacology, Vol. 6, pp. 215, (2015) (PubMed).

    Yang, Gao, Rao, Zhang, Ouyang, Yang: "Antisense oligonucleotide targeting matrix metalloproteinase-7 (MMP-7) changes the ultrastructure of human A549 lung adenocarcinoma cells." in: Ultrastructural pathology, Vol. 35, Issue 6, pp. 256-9, (2011) (PubMed).

    Yang, Shi, Li, Yi: "Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line." in: Oncology reports, Vol. 25, Issue 1, pp. 259-65, (2010) (PubMed).

    Pan, Zhang, Xu, Meng, Zhang, Xue, Han, Li: "Beta-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription." in: Histochemistry and cell biology, Vol. 134, Issue 3, pp. 285-95, (2010) (PubMed).

  • 抗原
    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
    别名
    MMP7 (MMP7 产品)
    别名
    MAT antibody, MPMM antibody, MMP-7 antibody, MPSL1 antibody, PUMP-1 antibody, matrilysin antibody, LOC727698 antibody, MMP7 antibody, Matrilysin antibody, matrix metallopeptidase 7 antibody, MMP7 antibody, Mmp7 antibody
    背景
    Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The MMP-7 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The MMP-7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP-7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, MMP-7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP-7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. MMP-7 is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.

    Synonyms: Matrilysin antibody|Matrilysin uterine antibody|Matrin antibody|Matrix Metalloproteinase 7 antibody|Matrix metalloproteinase-7 antibody|MMP 7 antibody|MMP-7 antibody|MMP7 antibody|MMP7_HUMAN antibody|MPSL1 antibody|PUMP 1 antibody|Pump 1 protease antibody|Pump-1 protease antibody|PUMP1 antibody|Uterine Matrilysin antibody|Uterine metalloproteinase antibody
    基因ID
    17393
    UniProt
    Q10738
    途径
    Production of Molecular Mediator of Immune Response
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