MMP7 抗体 (AA 1-267)
(8 references)-
- 抗原 See all MMP7 抗体
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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抗原表位
- AA 1-267
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Matrilysin(MMP7) detection. Tested with WB, IHC-P, ELISA in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Matrilysin(MMP7) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: matrix metallopeptidase 7 (matrilysin, uterine)
Protein Name: Matrilysin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MMP7 recombinant protein (Position: M1-K267). Human MMP7 shares 71% amino acid (aa) sequences identity with both mouse and rat MMP7.
- 亚型
- IgG
- Top Product
- Discover our top product MMP7 Primary Antibody
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anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 151-250) antibody
MMP7 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 1-267) antibodyMMP7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 1-264) antibodyMMP7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 1-267) antibodyMMP7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 18-267) antibodyMMP7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) antibodyMMP7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 18-267) antibodyMMP7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal H6 unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (C-Term) antibodyMMP7 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (C-Term) antibodyMMP7 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (AA 117-146) antibodyMMP7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MMP7 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).
: "Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells." in: International journal of oncology, Vol. 52, Issue 6, pp. 1787-1800, (2018) (PubMed).
: "5-Hydroxy-4'-Nitro-7-Propionyloxy-Genistein Inhibited Invasion and Metastasis via Inactivating Wnt/b-Catenin Signal Pathway in Human Endometrial Carcinoma Ji Endometrial Cells." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 3230-3243, (2018) (PubMed).
: "Growth differentiation factor 15 induces growth and metastasis of human liver cancer stem-like cells via AKT/GSK-3β/β-catenin signaling." in: Oncotarget, Vol. 8, Issue 10, pp. 16972-16987, (2017) (PubMed).
: "Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats." in: Frontiers in pharmacology, Vol. 6, pp. 215, (2015) (PubMed).
: "Antisense oligonucleotide targeting matrix metalloproteinase-7 (MMP-7) changes the ultrastructure of human A549 lung adenocarcinoma cells." in: Ultrastructural pathology, Vol. 35, Issue 6, pp. 256-9, (2011) (PubMed).
: "Effects of shRNA targeting maspin on invasion of gastric carcinoma SGC7901 cell line." in: Oncology reports, Vol. 25, Issue 1, pp. 259-65, (2010) (PubMed).
: "Beta-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription." in: Histochemistry and cell biology, Vol. 134, Issue 3, pp. 285-95, (2010) (PubMed).
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: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).
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- 抗原
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
- 别名
- MMP7 (MMP7 产品)
- 别名
- MAT antibody, MPMM antibody, MMP-7 antibody, MPSL1 antibody, PUMP-1 antibody, matrilysin antibody, LOC727698 antibody, MMP7 antibody, Matrilysin antibody, matrix metallopeptidase 7 antibody, MMP7 antibody, Mmp7 antibody
- 背景
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Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The MMP-7 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The MMP-7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP-7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, MMP-7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP-7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. MMP-7 is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.
Synonyms: Matrilysin antibody|Matrilysin uterine antibody|Matrin antibody|Matrix Metalloproteinase 7 antibody|Matrix metalloproteinase-7 antibody|MMP 7 antibody|MMP-7 antibody|MMP7 antibody|MMP7_HUMAN antibody|MPSL1 antibody|PUMP 1 antibody|Pump 1 protease antibody|Pump-1 protease antibody|PUMP1 antibody|Uterine Matrilysin antibody|Uterine metalloproteinase antibody - 基因ID
- 4316
- UniProt
- P09237
- 途径
- Production of Molecular Mediator of Immune Response
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