IKZF1 抗体 (C-Term)
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- 抗原 See all IKZF1 抗体
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
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抗原表位
- AA 428-459, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IKZF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for DNA-binding protein Ikaros(IKZF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- LKEEHRAYDL LRAASENSQD ALRVVSTSGE QM
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for DNA-binding protein Ikaros(IKZF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: IKAROS family zinc finger 1 (Ikaros)
Protein Name: DNA-binding protein Ikaros - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Ikaros (428-459aa LKEEHRAYDLLRAASENSQDALRVVSTSGEQM), different from the related mouse sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IKZF1 Primary Antibody
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anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-265) antibody
IKZF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-270) antibodyIKZF1 适用: 人 WB, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 415-444), (C-Term) antibodyIKZF1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24656 unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (C-Term) antibody (PE)IKZF1 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal 4E9 PE
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) antibodyIKZF1 适用: 人 WB, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Middle Region) antibodyIKZF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-477) antibodyIKZF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Internal Region) antibodyVerified IKZF1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (N-Term) antibodyIKZF1 适用: 小鼠 WB, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) antibodyIKZF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
- 别名
- IKZF1 (IKZF1 产品)
- 别名
- Hs.54452 antibody, IK1 antibody, IKAROS antibody, LYF1 antibody, PRO0758 antibody, ZNFN1A1 antibody, hIk-1 antibody, RGD1562979 antibody, ikaros antibody, znfn1a1 antibody, ik1 antibody, lyf1 antibody, hik-1 antibody, pro0758 antibody, hs.54452 antibody, MGC108252 antibody, 5832432G11Rik antibody, Ikaros antibody, LyF-1 antibody, Zfpn1a1 antibody, Znfn1a1 antibody, hlk-1 antibody, mKIAA4227 antibody, ikzf1 antibody, IKAROS family zinc finger 1 antibody, IKAROS family zinc finger 1 (Ikaros) antibody, IKZF1 antibody, Ikzf1 antibody, ikzf1 antibody
- 背景
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DNA-binding protein Ikaros is a protein that in humans is encoded by the IKZF1 gene. This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and are thought to function as dominant-negative factors.
Synonyms: CLL associated antigen KW 6 antibody|DNA-binding protein Ikaros antibody|hIk 1 antibody|Hs.54452 antibody|IK1 antibody|Ikaros (zinc finger protein) antibody|IKAROS antibody|IKAROS family zinc finger 1 (Ikaros) antibody|Ikaros family zinc finger protein 1 antibody| Ikzf1 antibody|IKZF1_HUMAN antibody|LYF1 antibody|Lymphoid transcription factor LyF-1 antibody|PRO0758 antibody|Zinc finger protein subfamily 1A 1 (Ikaros) antibody|Zinc finger protein subfamily 1A 1 antibody|Zinc finger protein, subfamily 1A, member 1 antibody| ZNFN1A1 antibody - 基因ID
- 10320
- UniProt
- Q13422
- 途径
- Production of Molecular Mediator of Immune Response
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