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GFAP 抗体 (AA 93-432)

Name: GFAP 抗体 (AA 93-432)
SKU: ABIN3043832
Availability: OutOfStock

GFAP 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Observed bind size: 49KD (GFAP 抗体 (AA 93-432))

Anti-GFAP Picoband antibody, IHC(P): Mouse Brain Tissue (GFAP 抗体 (AA 93-432))

IHC

Anti-GFAP Picoband antibody, IHC(P): Human meningioma Tissue (GFAP 抗体 (AA 93-432))

IHC

Anti-GFAP Picoband antibody, IHC(P): Rat Brain Tissue (GFAP 抗体 (AA 93-432))

IHC

4 images

(82 references)

产品编号 ABIN3043832

发货至: 中国

Datasheet as PDF

抗原 See all GFAP 抗体

GFAP (Glial Fibrillary Acidic Protein (GFAP))
抗原表位
30

27

26

16

12

9

9

9

8

7

7

6

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 93-432
适用
293

172

171

50

50

33

30

11

10

9

7

6

5

4

3

2

2

2

1

1

1

1

1
人, 大鼠, 小鼠
宿主
192

142

12

3

2

2
兔
Compatible Secondaries
克隆类型
197

156
多克隆
标记
164

27

23

16

11

7

7

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1
This GFAP antibody is un-conjugated
应用范围
270

127

92

79

73

59

46

28

26

26

22

18

13

8

8

4

4

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Glial fibrillary acidic protein(GFAP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Glial fibrillary acidic protein(GFAP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: glial fibrillary acidic protein
Protein Name: Glial fibrillary acidic protein

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human GFAP recombinant protein (Position: Q93-M432). Human GFAP shares 94% amino acid (aa) sequence identity with both mouse and rat GFAP.

亚型

IgG

Top Product

Discover our top product GFAP Primary Antibody
anti-Glial Fibrillary Acidic Protein (GFAP) (AA 51-150) antibody
GFAP 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (C-Term) antibody
GFAP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (AA 253-354) antibody
GFAP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (AA 1-430) antibody
GFAP 适用: 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C9 unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (AA 292-432) antibody
GFAP 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 小鼠 Monoclonal 1C91F1 unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) antibody
GFAP 适用: 大鼠, 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (pSer38) antibody
GFAP 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (C-Term) antibody
Verified GFAP 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) antibody
GFAP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) (AA 108-211) antibody
GFAP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for GFAP is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Daugherty, Chechneva, Mayrhofer, Deng: "The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis." in: Scientific reports, Vol. 6, pp. 22556, (2017) (PubMed).

Mi, Gao, Liu, Ye, Li, Jin, Yang, Yang: "Cyclin-dependent kinase inhibitor flavopiridol promotes remyelination in a cuprizone induced demyelination model." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 20, pp. 2780-91, (2017) (PubMed).

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Yang, Xie, Hu, Jiang, Shen, Schachner, Zhao: "CHL1 Is Expressed and Functions as a Malignancy Promoter in Glioma Cells." in: Frontiers in molecular neuroscience, Vol. 10, pp. 324, (2017) (PubMed).

Jiang, Luo, Qin, Ma, Li, Zhan, Zhang: "Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats." in: Frontiers in molecular neuroscience, Vol. 10, pp. 363, (2017) (PubMed).

Wang, Lin, Cao, Duan, Guan, Xu, Zhu, Xia: "Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice." in: Scientific reports, Vol. 7, Issue 1, pp. 16682, (2017) (PubMed).

Tang, Luo, Qiu, Zhang, Lu, Huang, Xu, Xu: "Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy." in: Scientific reports, Vol. 7, Issue 1, pp. 18110, (2017) (PubMed).

Yuan, Hu, Gao: "Brain Localization and Neurotoxicity Evaluation of Polysorbate 80-Modified Chitosan Nanoparticles in Rats." in: PLoS ONE, Vol. 10, Issue 8, pp. e0134722, (2016) (PubMed).

Cui, Li, Gai, She, Zhang, Xu, Chen, An, Ma, Wang: "Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus." in: Scientific reports, Vol. 5, pp. 12943, (2016) (PubMed).

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Zhu, Li, Luo, Wang, Li, Xie, Gao, Song, Su, Liang et al.: "Reversion of malignant phenotypes of human glioblastoma cells by β-elemene through β-catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related ..." in: Journal of translational medicine, Vol. 13, pp. 356, (2016) (PubMed).

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抗原

GFAP (Glial Fibrillary Acidic Protein (GFAP))

别名

GFAP (GFAP 产品)

别名

GFAP antibody, AI836096 antibody, cb345 antibody, etID36982.3 antibody, gfapl antibody, wu:fb34h11 antibody, wu:fk42c12 antibody, xx:af506734 antibody, zgc:110485 antibody, glial fibrillary acidic protein antibody, GFAP antibody, LOC100136168 antibody, gfap antibody, Gfap antibody

背景

Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. It is an intermediate filament(IF) protein that is expressed by numerous cell types of the central nervous system (CNS) including astrocytes, and ependymal cells. It is mapped to 17q21.31. GFAP is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell's cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells. This gene has been shown to play a role in mitosis by adjusting the filament network present in the cell. GFAP is necessary for many critical roles in the CNS. What's more, GFAP also plays a role in astrocyte-neuron interactions as well as cell-cell communication.

Synonyms: Astrocyte antibody|FLJ42474 antibody|FLJ45472 antibody|GFAP antibody|GFAP_HUMAN antibody|Glial Fibrillary Acidic Protein antibody|Intermediate filament protein antibody

基因ID

2670

UniProt

P14136