DAXX 抗体 (AA 56-345)
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- 抗原 See all DAXX 抗体
- DAXX (Death-Domain Associated Protein (DAXX))
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抗原表位
- AA 56-345
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAXX antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Death domain-associated protein 6(DAXX) detection. Tested with WB, IHC-P, ICC in Human,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Death domain-associated protein 6(DAXX) detection. Tested with WB, IHC-P, ICC in Human,Rat.
Gene Name: death-domain associated protein
Protein Name: Death domain-associated protein 6 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Daxx recombinant protein (Position: K56-R345). Human Daxx shares 88.3% and 88.6% amino acid (aa) sequence identity with mouse and rat Daxx, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product DAXX Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- DAXX (Death-Domain Associated Protein (DAXX))
- 别名
- DAXX (DAXX 产品)
- 别名
- BING2 antibody, DAP6 antibody, EAP1 antibody, LOC100226911 antibody, daxx antibody, si:dz179b20.7 antibody, wu:fd15c03 antibody, death domain associated protein antibody, Fas death domain-associated protein antibody, 28S ribosomal protein S29, mitochondrial antibody, death-domain associated protein antibody, death-associated protein 6 L homeolog antibody, DAXX antibody, Daxx antibody, LOC100226911 antibody, daxx.L antibody, daxx antibody
- 背景
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DAXX (death-domain associated protein) also known as DAP6 (Death-associated protein 6) or BING2, was first discovered through its cytoplasmic interaction with the classical death receptor Fas. Human DAXX encodes a 740-amino acid polypeptide containing a nuclear localization signal. Functional analyses by Yang et al. (1997) demonstrated that Daxx binds to the Fas death domain and enhances Fas-mediated apoptosis. The authors suggested that DAXX and FADD define 2 distinct apoptotic pathways downstream of Fas. The DAXX gene is mapped to human chromosome 6p21.3 by somatic cell hybrid panels and fluorescence in situ hybridization, a region containing the HLA and putative autoimmune disease genes. MSP58 overexpression relieved DAXX-mediated transcriptional repression. Immunoprecipitation and Western blot analysis with DAXX mutants showed that the N terminus of DAXX interacts with the C terminus of DMAP. Transient expression of DAXX or DMAP1 caused repression of glucocorticoid receptor-mediated transcription.
Synonyms: BING 2 antibody|BING2 antibody|CENP-C binding protein antibody|DAP 6 antibody|DAP6 antibody|Daxx antibody|DAXX antibody|DAXX_HUMAN antibody|Death associated protein 6 antibody|Death domain associated protein 6 antibody|Death domain associated protein antibody|Death domain-associated protein 6 antibody|EAP 1 antibody|EAP1 antibody|ETS1 associated protein 1 antibody|ETS1-associated protein 1 antibody|Fas binding protein antibody|Fas death domain associated protein antibody|Fas death domain-associated protein antibody|hDaxx antibody|MGC126245 antibody|MGC126246 antibody - 基因ID
- 1616
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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