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CD3 epsilon 抗体 (AA 23-207)

CD3E 适用: 人, 小鼠, 大鼠 WB, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

Anti-CD3 epsilon Picoband antibody, All lanes: Anti CD3 Epsilon at 0. (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, pb9093-6. (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, pb9093-7. (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, IHC(P): Human Tonsil Tissue (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, All lanes: Anti CD3 Epsilon at 0. (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, IHC(P): Rat Spleen Tissue (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, IHC(P): Mouse Spleen Tissue (CD3 epsilon 抗体 (AA 23-207))

Anti-CD3 epsilon Picoband antibody, pb9093IHC(F): Rat Spleen Tissue (CD3 epsilon 抗体 (AA 23-207))

8 images

(6 references)

产品编号 ABIN3043805

发货至: 中国

Datasheet as PDF

抗原 See all CD3 epsilon (CD3E) 抗体

CD3 epsilon (CD3E)
抗原表位
24

20

16

16

12

10

8

8

6

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 23-207
适用
227

157

51

41

18

8

8

8

7

4

4

4

4

3

3

3

3

3

3

1

1
人, 小鼠, 大鼠
宿主
137

122

34

23

20

8

1

1

1
兔
Compatible Secondaries
克隆类型
230

111

6
多克隆
标记
136

32

27

20

17

8

8

5

5

4

4

4

4

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD3 epsilon antibody is un-conjugated
应用范围
253

142

103

83

78

67

27

26

24

22

14

13

13

11

8

6

4

3

3

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

原理

Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD3 epsilon chain(CD3E) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD3 epsilon chain(CD3E) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: CD3e molecule, epsilon (CD3-TCR complex)
Protein Name: T-cell surface glycoprotein CD3 epsilon chain

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CD3 epsilon recombinant protein (Position: D23-I207). Human CD3 epsilon shares 65% amino acid (aa) sequence identity with mouse CD3 epsilon.

亚型

IgG
anti-CD3 epsilon (CD3E) antibody
CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E 适用: 人, Pig, 大鼠, 兔, Cow, 马, 豚鼠, 小鸡 FACS, WB, IF 宿主: 小鼠 Monoclonal PC3-188A unconjugated

anti-CD3 epsilon (CD3E) (AA 23-119) antibody
CD3E 适用: 人 FACS, WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal C3e-1931 unconjugated

anti-CD3 epsilon (CD3E) antibody
CD3E 适用: 人, 小鼠, 大鼠 FACS, IF, Func 宿主: 小鼠 Monoclonal RIV9 unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 25-207) antibody
CD3E 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 28-185) antibody
CD3E 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 23-207) antibody
CD3E 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-CD3 epsilon (CD3E) antibody
CD3E 适用: 人 WB, IHC, IF 宿主: 兔 Chimeric YTH 12-5 unconjugated Recombinant Antibody

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD3 epsilon is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Guo, Qian, Zhang: "The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis." in: BMC ophthalmology, Vol. 16, pp. 66, (2017) (PubMed).

Chen, Liu, Xu, Yang, Zhang, Zhang: "Effectiveness of immune therapy combined with chemotherapy on the immune function and recurrence rate of cervical cancer." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 1063-1067, (2015) (PubMed).

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Li, Geng, Yin, Chen, Yang, Wu, Li, Du, Schmidt, Przybylski: "Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients." in: Journal of translational medicine, Vol. 8, pp. 47, (2010) (PubMed).

Xie, Jia, He, Gao: "Morphological observation of tumor infiltrating immunocytes in human rectal cancer." in: World journal of gastroenterology, Vol. 12, Issue 11, pp. 1757-60, (2006) (PubMed).

Zhang, Chen, Lao, Huang: "Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients." in: World journal of gastroenterology, Vol. 10, Issue 10, pp. 1436-9, (2005) (PubMed).
抗原

CD3 epsilon (CD3E)

别名

CD3E (CD3E 产品)

背景

CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. It is mapped to 11q23.3. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.

Synonyms: CD3 epsilon antibody|CD3e antibody|CD3E antibody|CD3e antigen epsilon polypeptide (TiT3 complex) antibody|CD3E antigen epsilon polypeptide antibody|CD3E antigen, epsilon subunit antibody|CD3e molecule epsilon antibody|CD3e molecule, epsilon (CD3 TCR complex) antibody|CD3e molecule, epsilon (CD3-TCR complex) antibody|CD3E_HUMAN antibody|IMD18 antibody|T cell antigen receptor complex epsilon subunit of T3 antibody|T cell surface antigen T3/Leu 4 epsilon chain antibody|T cell surface glycoprotein CD3 epsilon chain antibody|T-cell surface antigen T3/Leu-4 epsilon chain antibody|T-cell surface glycoprotein CD3 epsilon chain antibody|T3E antibody|TCRE antibody

基因ID

916

UniProt

P07766

途径

TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway

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