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Aquaporin 4 抗体 (C-Term)

AQP4 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Anti- Aquaporin 4 Picoband antibody, Western blotting All lanes: Anti Aquaporin 4 at 0. (Aquaporin 4 抗体 (C-Term))

Anti- Aquaporin 4 Picoband antibody, IHC(P) IHC(P): Rat Brain Tissue (Aquaporin 4 抗体 (C-Term))

Anti- Aquaporin 4 Picoband antibody, IHC(P) IHC(P): Human Glioma Tissue (Aquaporin 4 抗体 (C-Term))

Anti- Aquaporin 4 Picoband antibody, IHC(F) IHC(F): Rat Brain Tissue (Aquaporin 4 抗体 (C-Term))

Anti- Aquaporin 4 Picoband antibody, IHC(F) IHC(F): Mouse Brain Tissue (Aquaporin 4 抗体 (C-Term))

Anti- Aquaporin 4 Picoband antibody, IHC(P): Rat Brain Tissue (Aquaporin 4 抗体 (C-Term))

Anti- Aquaporin 4 Picoband antibody, IHC(P) IHC(P): Mouse Brain Tissue (Aquaporin 4 抗体 (C-Term))

7 images

(5 references)

产品编号 ABIN3043789

发货至: 中国

Datasheet as PDF

抗原 See all Aquaporin 4 (AQP4) 抗体

Aquaporin 4 (AQP4)
抗原表位
20

16

6

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 295-323, C-Term
适用
68

61

60

4

4

1

1

1

1
人, 小鼠, 大鼠
宿主
77

18

1
兔
Compatible Secondaries
克隆类型
76

20
多克隆
标记
46

11

5

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Aquaporin 4 antibody is un-conjugated
应用范围
72

45

25

24

22

14

14

14

13

13

5

4

3

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Rabbit IgG polyclonal antibody for Aquaporin-4(AQP4) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.

序列

KPGVVHVIDV DRGEEKKGKD QSGEVLSSV

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Aquaporin-4(AQP4) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
Gene Name: aquaporin 4
Protein Name: Aquaporin-4

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 4 (295-323aa KPGVVHVIDVDRGEEKKGKDQSGEVLSSV), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

亚型

IgG

Top Product

Discover our top product AQP4 Primary Antibody
anti-Aquaporin 4 (AQP4) (AA 271-323) antibody
AQP4 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Aquaporin 4 (AQP4) (AA 178-317) antibody
AQP4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Aquaporin 4 (AQP4) (AA 244-323) antibody
AQP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Aquaporin 4 (AQP4) (AA 253-323) antibody
AQP4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Aquaporin 4 (AQP4) antibody
Microarray verified AQP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB430199 unconjugated

anti-Aquaporin 4 (AQP4) antibody
Microarray verified AQP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB287702 unconjugated

anti-Aquaporin 4 (AQP4) antibody
AQP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Aquaporin 4 (AQP4) (AA 258-27) antibody
AQP4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Aquaporin 4 (AQP4) (AA 177-304) antibody
AQP4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Aquaporin 4 (AQP4) (AA 179-314) antibody
AQP4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Han, Huang, Liu, Sha, Hu, Liu: "Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure." in: International journal of molecular sciences, Vol. 19, Issue 1, (2018) (PubMed).

Anzabi, Ardalan, Iversen, Rafati, Hansen, Østergaard: "Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4." in: Frontiers in cellular neuroscience, Vol. 12, pp. 19, (2018) (PubMed).

Wang, Bu, Zhang, Chen, Zhang, Bao: "Expression pattern of aquaporins in patients with primary nephrotic syndrome with edema." in: Molecular medicine reports, Vol. 12, Issue 4, pp. 5625-32, (2016) (PubMed).

Zhang, Chen, Dang, Liu, Ito, Sun: "Neuroprotective effects of total steroid saponins on cerebral ischemia injuries in an animal model of focal ischemia/reperfusion." in: Planta medica, Vol. 80, Issue 8-9, pp. 637-44, (2015) (PubMed).

Chen, Huang, Ruan, He, Li: "Ulinastatin attenuates cerebral ischemia-reperfusion injury in rats." in: International journal of clinical and experimental medicine, Vol. 7, Issue 5, pp. 1483-9, (2014) (PubMed).
抗原

Aquaporin 4 (AQP4)

别名

AQP4 (AQP4 产品)

别名

zgc:100922 antibody, si:ch211-192k9.1 antibody, AQP4 antibody, LOC100232616 antibody, HMIWC2 antibody, MIWC antibody, WCH4 antibody, AQP-4 antibody, AQP4.M23 antibody, MIWC2 antibody, Miwc antibody, aquaporin-4 antibody, aquaporin 4 antibody, aquaporin 4 L homeolog antibody, aqp4 antibody, AQP4 antibody, aqp4.L antibody, Aqp4 antibody

背景

Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells. The gene of AQP4 is mapped to 18q11.2-q12.1. Similar to other aquaporins, the AQP4 gene is composed of 4 exons encoding 127, 55, 27, and 92 amino acids separated by introns of 0.8, 0.3, and 5.2 kb. Unlike other aquaporins, an alternative coding initiation sequence (designated exon 0) was located 2.7 kb upstream of exon 1. When spliced together, M1 and the subsequent 10 amino acids are encoded by exon 0, the next 11 amino acids and M23 are encoded by exon 1. AQP4 is expressed in astrocytes and is upregulated by direct insult to the central nervous system. And AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis. It is abundant in mammalian brain and is concentrated in astrocytic foot processes at the blood-brain barrier.

Synonyms: AQP 4 antibody|AQP-4 antibody|AQP4 antibody|AQP4_HUMAN antibody|Aquaporin type 4 antibody| Aquaporin-4 antibody|Aquaporin4 antibody|HMIWC 2 antibody|HMIWC2 antibody| Mercurial insensitive water channel antibody|Mercurial-insensitive water channel antibody|MGC22454 antibody|MIWC antibody|WCH 4 antibody|WCH4 antibody

基因ID

361

UniProt

P55087

途径

Sensory Perception of Sound

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