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- 抗原 See all C5 抗体
- C5 (Complement Component 5 (C5))
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抗原表位
- AA 1-77
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Complement C5(C5) detection. Tested with WB, IHC-P in Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Complement C5(C5) detection. Tested with WB, IHC-P in Rat.
Gene Name: complement component 5
Protein Name: Complement C5 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived rat C5a recombinant protein (Position: D1-R77). Rat C5a shares 62% and 82% amino acid (aa) sequences identity with human and mouse C5a, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product C5 Primary Antibody
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anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody
C5 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 701-755) antibodyC5 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 253-281) antibodyC5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibodyC5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21866 unconjugated
anti-Complement Component 5 (C5) (C-Term) antibodyC5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibodyC5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 1550-1661) antibodyC5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, The detection limit for C5a is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- C5 (Complement Component 5 (C5))
- 别名
- C5 (C5 产品)
- 别名
- C5 antibody, LOC565774 antibody, C5a antibody, C5b antibody, CPAMD4 antibody, Hc antibody, RGD1561905 antibody, He antibody, complement C5 antibody, complement component 5 antibody, hemolytic complement antibody, C5 antibody, c5 antibody, Hc antibody
- 背景
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C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
Synonyms: Anaphylatoxin C5a analog antibody|Anaphylatoxin C5a antibody|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody|C5 antibody|C5a antibody|CO5_HUMAN antibody|Complement C5 alpha'' chain antibody|Complement C5 antibody|Complement component C5 antibody|Complement component C5a antibody|CPAMD 4 antibody|CPAMD4 antibody - 基因ID
- 362119
- UniProt
- P08650
- 途径
- Complement System, Carbohydrate Homeostasis
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