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TdT 抗体 (AA 316-509)

Name: TdT 抗体 (AA 316-509)
SKU: ABIN3043577
Availability: OutOfStock

DNTT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Anti-TdT Picoband antibody, All lanes: Anti TDT at 0. (TdT 抗体 (AA 316-509))

2 images

(9 references)

产品编号 ABIN3043577

发货至: 中国

Datasheet as PDF

抗原 See all TdT (DNTT) 抗体

TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
抗原表位
16

12

8

8

6

6

5

5

2

2

2

1

1

1

1

1

1

1
AA 316-509
适用
85

19

18

5

4

4

3

3

2

2

2

2
人
宿主
72

14
兔
Compatible Secondaries
克隆类型
69

17
多克隆
标记
40

8

7

5

5

5

2

2

2

2

2

2

2

2
This TdT antibody is un-conjugated
应用范围
52

44

10

9

8

6

6

4

3

2

2

1

1

1

1

1

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for DNA nucleotidylexotransferase(DNTT) detection. Tested with WB in Human.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for DNA nucleotidylexotransferase(DNTT) detection. Tested with WB in Human.
Gene Name: DNA nucleotidylexotransferase
Protein Name: DNA nucleotidylexotransferase

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human TdT recombinant protein (Position: K316-A509). Human TdT shares 81% amino acid (aa) sequence identity with mouse TdT.

亚型

IgG

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anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibody
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DNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H5 unconjugated

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DNTT 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-453R unconjugated Recombinant Antibody

anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 351-450) antibody
DNTT 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-509) antibody
DNTT 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Deoxynucleotidyltransferase, terminal (DNTT) (Internal Region) antibody
DNTT 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Deoxynucleotidyltransferase, terminal (DNTT) antibody
DNTT 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Deoxynucleotidyltransferase, terminal (DNTT) (C-Term) antibody
DNTT 适用: 人, 大鼠, 猴, 马, 犬, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated

anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 32-81) antibody
DNTT 适用: 人, 小鼠, 大鼠, 马, 犬, Cow, Pig, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TdT is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Yang, Zhang, Ding, Huang, Chen, Wu, Wang, Wang, Chen: "Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer." in: British journal of cancer, Vol. 110, Issue 5, pp. 1288-97, (2014) (PubMed).

Zhang, Pei, Ru, Li, Liu: "Bone morphogenetic protein 7 upregulates the expression of nestin and glial fibrillary acidic protein in rats with cerebral ischemia-reperfusion injury." in: Biomedical reports, Vol. 1, Issue 6, pp. 895-900, (2014) (PubMed).

Tochinai, Ando, Suzuki, Suzuki, Nagata, Hata, Uchida, Kobayashi, Kado, Kaneko: "Histopathological studies of microtubule disassembling agent-induced myocardial lesions in rats." in: Experimental and toxicologic pathology : official journal of the Gesellschaft fu?r Toxikologische Pathologie, Vol. 65, Issue 6, pp. 737-43, (2013) (PubMed).

Zeng, Ke, Song, Yao, Hu, Zhang, Li, Yin: "Annexin A3 is associated with a poor prognosis in breast cancer and participates in the modulation of apoptosis in vitro by affecting the Bcl-2/Bax balance." in: Experimental and molecular pathology, Vol. 95, Issue 1, pp. 23-31, (2013) (PubMed).

Xi, Wang, Ye, Luo, Ning: "Combined adenovirus-mediated artificial microRNAs targeting mfgl2, mFas, and mTNFR1 protect against fulminant hepatic failure in mice." in: PLoS ONE, Vol. 8, Issue 11, pp. e82330, (2013) (PubMed).

Gong, Zheng, Wang, Chen, Pang, Hu, Cao: "Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model." in: World journal of gastroenterology, Vol. 18, Issue 35, pp. 4934-43, (2012) (PubMed).

Luo, Xia: "A small dose of hydrogen peroxide enhances tumor necrosis factor-alpha toxicity in inducing human vascular endothelial cell apoptosis: reversal with propofol." in: Anesthesia and analgesia, Vol. 103, Issue 1, pp. 110-6, table of contents, (2006) (PubMed).

Luo, Xia, Ansley, Ouyang, Granville, Li, Xia, Zhou, Liu: "Propofol dose-dependently reduces tumor necrosis factor-alpha-Induced human umbilical vein endothelial cell apoptosis: effects on Bcl-2 and Bax expression and nitric oxide generation." in: Anesthesia and analgesia, Vol. 100, Issue 6, pp. 1653-9, (2005) (PubMed).

Xu, Liu, Gao, Zhang, Wang, Cao: "Possible mechanisms of the protection of ginsenoside Re against MPTP-induced apoptosis in substantia nigra neurons of Parkinson's disease mouse model." in: Journal of Asian natural products research, Vol. 7, Issue 3, pp. 215-24, (2004) (PubMed).
抗原

TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

别名

DNTT (DNTT 产品)

别名

TdT antibody, TDT antibody, BB160593 antibody, Tdt antibody, dntt-A antibody, dntt antibody, DNA nucleotidylexotransferase antibody, deoxynucleotidyltransferase, terminal antibody, DNA nucleotidylexotransferase L homeolog antibody, terminal deoxynucleotidyl transferase antibody, DNTT antibody, dntt antibody, Dntt antibody, dntt.L antibody, tdt antibody

背景

Terminal Deoxynucleotidyl Transferase, also known as TDT and terminal transferase, is a unique DNA polymerase without template direction catalyzes the addition of deoxyribonucleotides onto the 3-prime-hydroxyl end of DNA primers. Its gene is mapped to the region 10q23-q24. And TDT cDNA contains an open reading frame of 1,530 basepairs corresponding to a protein containing 510 amino acids. TDT may be responsible for inserting nucleotides (N regions) at the V(H)-D and D-J(H) junctions of immunoglobulin genes. The enzyme is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells. Additionally, TDT catalyses the addition of nucleotides to the 3' terminus of a DNA molecule. Unlike most DNA polymerases it does not require a template. The preferred substrate of this enzyme is a 3'-overhang, but it can also add nucleotides to blunt or recessed 3' ends. Cobalt is a necessary cofactor.

Synonyms: Deoxynucleotidyltransferase terminal antibody|DNA nucleotidylexotransferase antibody|DNTT antibody|Nucleosidetriphosphate DNA deoxynucleotidylexotransferase antibody|TDT antibody|TDT_HUMAN antibody|Terminal addition enzyme antibody|Terminal deoxynucleotidyltransferase antibody|Terminal deoxyribonucleotidyltransferase antibody|Terminal transferase antibody

基因ID

1791

UniProt

P04053

途径

DNA Damage Repair