RRM2 抗体 (N-Term)
(1 reference)-
- 抗原 See all RRM2 抗体
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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抗原表位
- AA 1-33, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RRM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Ribonucleoside-diphosphate reductase subunit M2(RRM2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENT
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Ribonucleoside-diphosphate reductase subunit M2(RRM2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ribonucleotide reductase M2
Protein Name: Ribonucleoside-diphosphate reductase subunit M2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human RRM2 (1-33aa MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENT), different from the related mouse and rat sequences by eight amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RRM2 Primary Antibody
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anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-110) antibody
RRM2 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (Regulatory Subunit) antibodyKO Validated RRM2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibodyRRM2 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-111) antibodyRRM2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
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: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
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- 抗原
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- 别名
- RRM2 (RRM2 产品)
- 别名
- R2 antibody, RR2 antibody, RR2M antibody, AA407299 antibody, rrm2 antibody, rr2m antibody, cb111 antibody, chunp6884 antibody, r2 antibody, ribonucleotide reductase regulatory subunit M2 antibody, ribonucleotide reductase M2 antibody, ribonucleotide reductase M2, gene 2 L homeolog antibody, ribonucleotide reductase M2, gene 1 antibody, ribonucleotide reductase M2 polypeptide antibody, RRM2 antibody, Rrm2 antibody, rrm2.2.L antibody, rrm2.1 antibody, rrm2 antibody
- 背景
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Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene. It is mapped to 2p25-p24. This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms which differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
Synonyms: R2 antibody|Ribonucleoside-diphosphate reductase subunit M2 antibody|Ribonucleotide reductase M2 antibody|Ribonucleotide reductase M2 polypeptide antibody|Ribonucleotide reductase M2 subunit antibody|Ribonucleotide reductase small chain antibody|Ribonucleotide reductase small subunit antibody|RIR2_HUMAN antibody|RR2 antibody|RR2M antibody|RRM2 antibody - 基因ID
- 6241
- UniProt
- P31350
- 途径
- Mitotic G1-G1/S Phases
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