Dystrophin 抗体 (AA 3076-3404)
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- 抗原 See all Dystrophin (DMD) 抗体
- Dystrophin (DMD)
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抗原表位
- AA 3076-3404
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Dystrophin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Dystrophin(DMD) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Dystrophin(DMD) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: dystrophin
Protein Name: Dystrophin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.
- 亚型
- IgG
- Top Product
- Discover our top product DMD Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human,Mouse, Rat , The detection limit for Dystrophin is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Dystrophin (DMD)
- 别名
- DMD (DMD 产品)
- 背景
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Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (myofiber). It is a cohesive protein, linking actin filaments to another support protein that resides on the inside surface of each muscle fiber's plasma membrane (sarcolemma).
Synonyms: Apo dystrophin antibody|BMD antibody|CMD3B antibody|DMD antibody|DMD_HUMAN antibody|Duchenne muscular dystrophy protein antibody|DXS142 antibody|DXS164 antibody|DXS206 antibody|DXS230 antibody|DXS239 antibody|DXS268 antibody|DXS269 antibody|DXS270 antibody|DXS272 antibody|Dystrophin antibody|Muscular dystrophy Duchenne and Becker types antibody - 基因ID
- 1756
- UniProt
- P11532
- 途径
- Skeletal Muscle Fiber Development
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