电话:: +86 (0512) 65829739
传真:: +86 (010) 6788 5057
电子邮件:: orders@antibodies-online.cn

我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Desmin 抗体 (AA 1-304)

DES 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Anti-Desmin Picoband antibody, All lanes: Anti Desmin at 0. (Desmin 抗体 (AA 1-304))

Western Blotting (WB) image for anti-Desmin (DES) (AA 1-304) antibody (ABIN3043265) (Desmin 抗体 (AA 1-304))

Anti-Desmin Picoband antibody, IHC(P): Rat Cardiac Muscle Tissue (Desmin 抗体 (AA 1-304))

Anti-Desmin Picoband antibody, IHC(P): Human Intestinal Cancer Tissue (Desmin 抗体 (AA 1-304))

Anti-Desmin Picoband antibody, IHC(P): Mouse Skeletal Muscle Tissue (Desmin 抗体 (AA 1-304))

Anti-Desmin Picoband antibody, IHC(F): Mouse Cardiac Muscle Tissue (Desmin 抗体 (AA 1-304))

Anti-Desmin Picoband antibody, IHC(F): Rat Cardiac Muscle Tissue (Desmin 抗体 (AA 1-304))

7 images

(22 references)

产品编号 ABIN3043265

发货至: 中国

Datasheet as PDF

抗原 See all Desmin (DES) 抗体

Desmin (DES)
抗原表位
16

16

16

16

15

14

7

5

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-304
适用
157

84

82

34

18

13

11

9

8

5

4

4

2

1
人, 小鼠, 大鼠
宿主
117

39

2
兔
Compatible Secondaries
克隆类型
112

47
多克隆
标记
78

8

8

7

5

3

3

3

3

3

3

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This Desmin antibody is un-conjugated
应用范围
116

71

53

44

27

20

14

13

9

8

7

3

2

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Rabbit IgG polyclonal antibody for Desmin(DES) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Desmin(DES) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
Gene Name: desmin
Protein Name: Desmin

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Desmin recombinant protein (Position: M1-T304). Human Desmin shares 97% amino acid (aa) sequences identity with both mouse and rat Desmin.

亚型

IgG

Top Product

Discover our top product DES Primary Antibody
anti-Desmin (DES) (C-Term) antibody
Verified DES 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Desmin (DES) (AA 261-360) antibody
DES 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Desmin (DES) antibody
DES 适用: 人 WB, IHC (p), IF, FACS, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-Desmin (DES) (AA 121-470) antibody
DES 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Desmin (DES) antibody
DES 适用: 人, 小鼠, 大鼠, 小鸡, Hamster, Pig, 犬, 兔, 斑马鱼 WB, IHC, IHC (fro) 宿主: 小鼠 Monoclonal RD301 unconjugated

anti-Desmin (DES) antibody
DES 适用: 人, 小鼠, 大鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 7A6 unconjugated

anti-Desmin (DES) antibody
DES 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 3E1G4 unconjugated

anti-Desmin (DES) (C-Term) antibody
DES 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Desmin (DES) (AA 361-470) antibody
DES 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D12 unconjugated

anti-Desmin (DES) antibody
DES 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-651M unconjugated Recombinant Antibody

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Desmin is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Huang, Chen, Guo, Chen, Zhang, Chen, Wang: "Interleukin‑10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5700-5707, (2018) (PubMed).

Liu, Du, Zhu, Zhang, Sun, Liu, Li, Wang, Du: "Identification of apoptosis-related microRNAs and their target genes in myocardial infarction post-transplantation with skeletal myoblasts." in: Journal of translational medicine, Vol. 13, pp. 270, (2016) (PubMed).

Jiang, Zhang, Fang, Zhang, Lu, Zhu, Cheng, Ai, Zhou, Li, Fang, Yao: "Analgesic effects of Chinese Tuina massage in a rat model of pain." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1367-1374, (2016) (PubMed).

Zhang, Deng, Wen, Chen, Liu, Ye, Huang, Jiang, Xiong: "PPAR? and MyoD are differentially regulated by myostatin in adipose-derived stem cells and muscle satellite cells." in: Biochemical and biophysical research communications, Vol. 458, Issue 2, pp. 375-80, (2015) (PubMed).

Gao, Zhi, Yang, Li, Yan, Wang: "Low dose of IGF-I increases cell size of skeletal muscle satellite cells via Akt/S6K signaling pathway." in: Journal of cellular biochemistry, Vol. 116, Issue 11, pp. 2637-48, (2015) (PubMed).

Sondag, Salihoglu, Lababidi, Crowder, Moussa, Abdelmagid, Safadi: "Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts." in: Journal of cellular physiology, Vol. 229, Issue 7, pp. 955-66, (2014) (PubMed).

Wei, Yang, Wang, Xu, Liang, Zhou: "Sodium ferulate lowers portal pressure in rats with secondary biliary cirrhosis through the RhoA/Rho-kinase signaling pathway: a preliminary study." in: International journal of molecular medicine, Vol. 34, Issue 5, pp. 1257-67, (2014) (PubMed).

Pan, Chen, Huang, Yao, Ma: "Transforming growth factor ?1 induces the expression of collagen type I by DNA methylation in cardiac fibroblasts." in: PLoS ONE, Vol. 8, Issue 4, pp. e60335, (2013) (PubMed).

Wu, Gu, Zhao, Tan, Chen, Zhu, Zhang: "Derivation of multipotent nestin(+)/CD271 (-)/STRO-1 (-) mesenchymal-like precursors from human embryonic stem cells in chemically defined conditions." in: Human cell, Vol. 26, Issue 1, pp. 19-27, (2013) (PubMed).

Liu, Liu, Xu, Wang, Zhu, Li, Wang, Liu, Ma, Wu: "Neurotransmitter noradrenaline downregulate cytoskeletal protein expression of VSMCs." in: Experimental and molecular pathology, Vol. 94, Issue 1, pp. 79-83, (2013) (PubMed).

Yan, Gan, Yang, Sun: "The proliferation and differentiation characteristics of co-cultured porcine preadipocytes and muscle satellite cells in vitro." in: Molecular biology reports, Vol. 40, Issue 4, pp. 3197-202, (2013) (PubMed).

Liu, Wang, Du, Liu, Liu, Zhang, Zhang, Hou, Liu, Zhang, Yu: "Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells." in: PLoS ONE, Vol. 8, Issue 3, pp. e58883, (2013) (PubMed).

Qian, Qian, Zhang, Zhu, Yan, Ye, Peng, Li, Xu, Sun, Xu: "5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase." in: Stem cells and development, Vol. 21, Issue 1, pp. 67-75, (2012) (PubMed).

Liu, Wang, Yu, Zhang, Chen, Jin, Dai, Li, Xu: "Injection of duck recombinant follistatin fusion protein into duck muscle tissues stimulates satellite cell proliferation and muscle fiber hypertrophy." in: Applied microbiology and biotechnology, Vol. 94, Issue 5, pp. 1255-63, (2012) (PubMed).

Wang, Yang, Yang, Shu, Wang, Jiang, Yuan, Wu: "The differential proliferative ability of satellite cells in Lantang and Landrace pigs." in: PLoS ONE, Vol. 7, Issue 3, pp. e32537, (2012) (PubMed).

Zhang, Zheng, Yu, Min, Yu, Ye, Xie, Zhang: "Lentiviral vector-mediated down-regulation of IL-17A receptor in hepatic stellate cells results in decreased secretion of IL-6." in: World journal of gastroenterology, Vol. 18, Issue 28, pp. 3696-704, (2012) (PubMed).

Longxi, Buwu, Yuan, Sinan: "Expression of p53 in the effects of artesunate on induction of apoptosis and inhibition of proliferation in rat primary hepatic stellate cells." in: PLoS ONE, Vol. 6, Issue 10, pp. e26500, (2011) (PubMed).

Liu, Li, Chen, Cao, Zhang, Yu, Xu, He, Wang: "Characterization of in vitro cultured myoblasts isolated from duck (Anas platyrhynchos) embryo." in: Cytotechnology, Vol. 63, Issue 4, pp. 399-406, (2011) (PubMed).

Xu, Qian, Zhu, Zhang, Yan, Wang, Xu: "Isolation of cancer stem cells from transformed human mesenchymal stem cell line F6." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 11, pp. 1181-90, (2010) (PubMed).

Wang, Fan, Zhang, Liu, Sun, Wang: "Compatibility of hyaluronic acid hydrogel and skeletal muscle myoblasts." in: Biomedical materials (Bristol, England), Vol. 4, Issue 2, pp. 25011, (2009) (PubMed).

show more references
抗原

Desmin (DES)

别名

DES (DES 产品)

别名

DES antibody, des-b antibody, MGC80853 antibody, des antibody, csm1 antibody, csm2 antibody, desm antibody, cmd1i antibody, MGC75911 antibody, LOC100220724 antibody, desmin antibody, cb290 antibody, fb59a12 antibody, wu:fb59a12 antibody, zgc:109859 antibody, CSM1 antibody, CSM2 antibody, LGMD2R antibody, wu:fc11d08 antibody, zgc:154009 antibody, des-a antibody, MGC52614 antibody, desmin antibody, desmin, gene 1 L homeolog antibody, desmin, gene 1 antibody, desmin a antibody, desmin b antibody, desmin, gene 1 S homeolog antibody, desmin, gene 2 S homeolog antibody, DES antibody, des.1.L antibody, des.1 antibody, des antibody, desma antibody, Des antibody, desmb antibody, des.1.S antibody, des.2.S antibody

背景

DES, also called desmin, is a protein that in humans is encoded by the DES gene, and this gene is mapped to 2q35. DES is the muscle-specific member of the intermediate filament (IF) protein family. It is one of the earliest myogenic markers, both in heart and somites, and is expressed in satellite stem cells and replicating myoblasts. DES is very important in muscle cell architecture and structure since it connects many components of the cytoplasm. It may be also play an important role in mitochondria function. What's more, DES provides attachments between the terminal Z disc and membrane-associated proteins to form a force-transmitting system that parallels the thin filaments at myotendinous junctions.

Synonyms: CMD1I antibody|CSM1 antibody|CSM2 antibody|DES antibody|DESM_HUMAN antibody|Desmin antibody|FLJ12025 antibody|FLJ39719 antibody|FLJ41013 antibody|FLJ41793 antibody|Intermediate filament protein antibody|OTTHUMP00000064865 antibody

基因ID

1674

UniProt

P17661

You are here: