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CD11b 抗体 (AA 17-382)

Name: CD11b 抗体 (AA 17-382)
SKU: ABIN3043258
Availability: OutOfStock

ITGAM 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti-CD11b Picoband antibody , All lanes: Anti CD11B at 0. (CD11b 抗体 (AA 17-382))

Anti-CD11b Picoband antibody , IHC(P): Rat Spleen Tissue (CD11b 抗体 (AA 17-382))

IHC

Anti-CD11b Picoband antibody , IHC(P): Human Tonsil Tissue (CD11b 抗体 (AA 17-382))

IHC

Anti-CD11b Picoband antibody , IHC(P): Mouse Spleen Tissue (CD11b 抗体 (AA 17-382))

IHC

4 images

(6 references)

产品编号 ABIN3043258

发货至: 中国

Datasheet as PDF

抗原 See all CD11b (ITGAM) 抗体

CD11b (ITGAM) (Integrin alpha M (ITGAM))
抗原表位
16

14

8

6

6

5

5

5

4

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 17-382
适用
264

175

65

31

20

19

17

14

11

10

7

4

4

2

2

1
人, 小鼠, 大鼠
宿主
148

111

105

2

1

1
兔
Compatible Secondaries
克隆类型
270

94

2
多克隆
标记
121

41

29

27

19

9

7

7

5

5

5

5

5

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This CD11b antibody is un-conjugated
应用范围
280

86

81

78

59

45

37

25

23

18

14

14

8

6

5

5

4

4

3

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Integrin alpha-M(ITGAM) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Integrin alpha-M(ITGAM) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: integrin, alpha M (complement component 3 receptor 3 subunit)
Protein Name: Integrin alpha-M

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CD11b recombinant protein (Position: F17-T382). Human CD11b shares 79% and 61% amino acid (aa) sequences identity with mouse and rat CD11b, respectively.

亚型

IgG

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anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM 适用: 人, 小鼠, 大鼠 FACS 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 77-180) antibody
ITGAM 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibody
ITGAM 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB17991 unconjugated

anti-Integrin alpha M (ITGAM) (AA 31-160) antibody
ITGAM 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal ITGAM-3338 unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal ITGAM-3340 unconjugated

anti-Integrin alpha M (ITGAM) antibody (FITC)
ITGAM 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-174 FITC

anti-Integrin alpha M (ITGAM) antibody (Biotin)
ITGAM 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-174 Biotin

anti-Integrin alpha M (ITGAM) antibody (PE)
ITGAM 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-174 PE

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Mu, Jing, Guo: "Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." in: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).

Ren, Zhang, Zhou, Sun, Zhang, Wei, Zhang, Si: "Tanshinone IIA prevents the loss of nigrostriatal dopaminergic neurons by inhibiting NADPH oxidase and iNOS in the MPTP model of Parkinson's disease." in: Journal of the neurological sciences, Vol. 348, Issue 1-2, pp. 142-52, (2015) (PubMed).

Zhao, Wang, Wang, Sun, Yang, Qiu, Wu, Zhang, Li, Zhang, Zhao, Zou, Ge: "CXCR6 deficiency ameliorated myocardial ischemia/reperfusion injury by inhibiting infiltration of monocytes and IFN-?-dependent autophagy." in: International journal of cardiology, Vol. 168, Issue 2, pp. 853-62, (2013) (PubMed).

Yuan, Su, Pu, Liu, Chen, Zhu, Zhu, Zhang, He: "Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment." in: British journal of pharmacology, Vol. 166, Issue 2, pp. 749-63, (2012) (PubMed).

Leng, Zhan, Wang, Liu, Gong, Gao, Wu, Wang, Zhao, Wang, Zhang, Pang, Qian: "Anti-heat shock protein 70 autoantibody epitope changes and BD091 promotes atherosclerosis in rats." in: Cell stress & chaperones, Vol. 15, Issue 6, pp. 947-58, (2011) (PubMed).

Shi, Xun, Yue, Zhang, Ren, Wang, Wu, Shi, Yang, Lei: "Cloning, characterization, and expression analysis of goat (Capra hircus) phospholipid hydroperoxide glutathione peroxidase (PHGPx)." in: International journal of biological sciences, Vol. 6, Issue 4, pp. 316-26, (2010) (PubMed).
抗原

CD11b (ITGAM) (Integrin alpha M (ITGAM))

别名

ITGAM (ITGAM 产品)

背景

Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). It is mapped to 16p11.2. ITGAM has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. What's more, ITGAM probably recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.

Synonyms: Antigen CD11b p170 antibody|CD11 antigen like family member B antibody|CD11 antigen-like family member B antibody|CD11b antibody|CD11b/CD18 antibody|CD49d antibody|Cell surface glycoprotein MAC-1 subunit alpha antibody|Complement component 3 receptor 3 subunit antibody|Complement Component Receptor 3 Alpha antibody|Complement receptor type 3, alpha subunit antibody|CR 3 alpha chain antibody|CR-3 alpha chain antibody|CR3 antibody|CR3A antibody|F730045J24Rik antibody|Integrin Alpha M antibody|Integrin alpha M chain antibody|Integrin alpha-M antibody|Integrin beta 2 alpha subunit antibody|ITAM_HUMAN antibody|ITGAM antibody|Leukocyte adhesion receptor MO1 antibody|Ly-40 antibody|MAC 1 antibody|Mac-1a antibody|MAC1 antibody|Mac1, alpha subunit antibody|MAC1A antibody|Macrophage antigen alpha polypeptide antibody|MGC117044 antibody|Mo1, alpha subunit antibody|MO1A antibody|Neutrophil adherence receptor alpha M subunit antibody|Neutrophil adherence receptor antibody|SLEB6 antibody

基因ID

3684

UniProt

P11215

途径

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation