Cadherin 5 抗体 (C-Term)
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- 抗原 See all Cadherin 5 (CDH5) 抗体
- Cadherin 5 (CDH5)
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抗原表位
- AA 766-784, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cadherin 5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Cadherin-5(CDH5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- RFKMLAELYG SDPREELLY
- 交叉反应 (详细)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Cadherin-5(CDH5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cadherin 5, type 2(vascular endothelium)
Protein Name: Cadherin-5 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human VE Cadherin(766-784aa RFKMLAELYGSDPREELLY), different from the related mouse and rat sequences by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CDH5 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21." in: International journal of biological sciences, Vol. 13, Issue 7, pp. 868-877, (2018) (PubMed).
: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, (2014) (PubMed).
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Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21." in: International journal of biological sciences, Vol. 13, Issue 7, pp. 868-877, (2018) (PubMed).
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- 抗原
- Cadherin 5 (CDH5)
- 别名
- CDH5 (CDH5 产品)
- 别名
- 7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody
- 背景
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CDH5(Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al.(1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.
Synonyms: 7B 4 antibody|7B4 antibody|7B4 antigen antibody|CADH5_HUMAN antibody|Cadherin 5 antibody|Cadherin 5 type 2 antibody|Cadherin 5, type 2(vascular endothelium) antibody|Cadherin 5, type 2, VE cadherin(vascular epithelium) antibody|cadherin, vascular endothelial antibody|cadherin, vascular endothelial, 1 antibody|Cadherin-5 antibody|Cadherin5 antibody|CD 144 antibody|CD144 antibody|CD144 antigen antibody|CDH 5 antibody|CDH5 antibody|CDH5 protein antibody|Endothelial specific cadherin antibody|FLJ17376 antibody|OTTHUMP00000174777 antibody|Vascular endothelial cadherin antibody|Vascular epithelium cadherin antibody|VE Cad antibody|VE-cadherin antibody|VEC antibody - UniProt
- P33151
- 途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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