PFN2 抗体 (C-Term)
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- 抗原 See all PFN2 抗体
- PFN2 (Profilin 2 (PFN2))
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抗原表位
- AA 125-140, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PFN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Profilin-2(PFN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- NKKAYSMAKY LRDSGF
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Profilin-2(PFN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: profilin 2
Protein Name: Profilin-2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Profilin 2(125-140aa NKKAYSMAKYLRDSGF), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product PFN2 Primary Antibody
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anti-Profilin 2 (PFN2) (AA 5-140) antibody
PFN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) antibodyPFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) (C-Term) antibodyPFN2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) (AA 41-140) antibodyPFN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G3 unconjugated
anti-Profilin 2 (PFN2) (AA 51-140) antibodyPFN2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) (AA 1-140) antibodyPFN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- PFN2 (Profilin 2 (PFN2))
- 别名
- PFN2 (PFN2 产品)
- 别名
- D3S1319E antibody, PFL antibody, Pfn antibody, Profilin2 antibody, XProfilin2 antibody, PFN2 antibody, PRO2 antibody, Profilin-2 antibody, pfl antibody, d3s1319e antibody, profilin-2 antibody, F17A13.170 antibody, F17A13_170 antibody, PRF2 antibody, PROFILIN antibody, PROFILIN 2 antibody, profilin 2 antibody, wu:fb01g08 antibody, wu:fb54f09 antibody, wu:fd58f06 antibody, profilin 2 antibody, profilin 2 L homeolog antibody, profilin homolog 2 antibody, Profilin-2 antibody, PFN2 antibody, Pfn2 antibody, pfn2.L antibody, prf2 antibody, pfn2 antibody, pfn-2 antibody
- 背景
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Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Synonyms: D3S1319E antibody|PFL antibody|PFN 2 antibody|PFN2 antibody|PROF2_HUMAN antibody|Profilin II antibody|Profilin-2 antibody|Profilin2 antibody|ProfilinII antibody - UniProt
- P35080
- 途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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