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CTGF 抗体 (AA 58-349)

Name: CTGF 抗体 (AA 58-349)
SKU: ABIN3042771
Availability: OutOfStock

CTGF 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Connective Tissue Growth Factor (CTGF) (AA 58-349) antibody (ABIN3042771) (CTGF 抗体 (AA 58-349))

Anti- CTGF Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (CTGF 抗体 (AA 58-349))

IHC

2 images

(18 references)

产品编号 ABIN3042771

发货至: 中国

Datasheet as PDF

抗原 See all CTGF 抗体

CTGF (Connective Tissue Growth Factor (CTGF))
抗原表位
16

12

8

7

7

7

6

6

6

6

5

5

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1
AA 58-349
适用
115

57

44

3

3

1

1

1
人, 大鼠
宿主
109

32

3

2
兔
Compatible Secondaries
克隆类型
114

32
多克隆
标记
67

25

19

7

5

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CTGF antibody is un-conjugated
应用范围
114

67

53

21

19

18

16

15

13

13

13

5

3

3

3

3

3

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Connective tissue growth factor(CTGF) detection. Tested with WB, IHC-P in Human,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Connective tissue growth factor(CTGF) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: connective tissue growth factor
Protein Name: Connective tissue growth factor

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CTGF recombinant protein (Position: R58-A349). Human CTGF shares 95.5% and 95.9% amino acid (aa) sequence identity with mouse and rat CTGF, respectively.

亚型

IgG

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CTGF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

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CTGF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C11 unconjugated

anti-Connective Tissue Growth Factor (CTGF) (AA 27-349) antibody
CTGF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Connective Tissue Growth Factor (CTGF) (AA 248-349) antibody
CTGF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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CTGF 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal unconjugated

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CTGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A7 unconjugated

anti-Connective Tissue Growth Factor (CTGF) (AA 111-123) antibody
Verified CTGF 适用: 人, 小鼠 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Connective Tissue Growth Factor (CTGF) (AA 27-349) antibody
CTGF 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Connective Tissue Growth Factor (CTGF) (AA 248-349) antibody
CTGF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Lu, Kang, Hu, Tang, Zhou, Yu, Xu: "Angiotensin-(1-7) relieved renal injury induced by chronic intermittent hypoxia in rats by reducing inflammation, oxidative stress and fibrosis." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 1, pp. e5594, (2017) (PubMed).

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Zhang, Li, Zheng, Lin, Zhang, Zhang: "Inhibition of angiogenesis by arsenic trioxide via TSP-1-TGF-β1-CTGF-VEGF functional module in rheumatoid arthritis." in: Oncotarget, Vol. 8, Issue 43, pp. 73529-73546, (2017) (PubMed).

Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

Bai, Li, Zhao, Liu, Wang, Lian, Zhao, Wang: "PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor." in: Oncotarget, Vol. 8, Issue 67, pp. 111642-111655, (2017) (PubMed).

Cheng, Xiao, Ainiwaer, Wang, Wu, Mao, Yang, Bao: "Molecular responses of radiation-induced liver damage in rats." in: Molecular medicine reports, Vol. 11, Issue 4, pp. 2592-600, (2015) (PubMed).

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Jin, Shi, Zou, Miao, Sun, Li: "Fenugreek Prevents the Development of STZ-Induced Diabetic Nephropathy in a Rat Model of Diabetes." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 259368, (2014) (PubMed).

Wang, Zhuang, Gao, Zhang, Yang: "Increased expression of CCN2 in the red flashing light-induced myopia in guinea pigs." in: BioMed research international, Vol. 2013, pp. 761823, (2014) (PubMed).

Guo, Qi, Yu, Du, Wu, Liu: "Effect of exenatide on the cardiac expression of adiponectin receptor 1 and NADPH oxidase subunits and heart function in streptozotocin-induced diabetic rats." in: Diabetology & metabolic syndrome, Vol. 6, Issue 1, pp. 29, (2014) (PubMed).

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Wang, Li, Lu, Zhao, Xu: "Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats." in: Croatian medical journal, Vol. 54, Issue 2, pp. 171-9, (2013) (PubMed).

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Wang, Hui, Fan, Xiong, Sun: "Filtering bleb area and intraocular pressure following subconjunctival injection of CTGF antibody after glaucoma filtration surgery in rabbits." in: International journal of ophthalmology, Vol. 4, Issue 5, pp. 480-3, (2012) (PubMed).

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抗原

CTGF (Connective Tissue Growth Factor (CTGF))

别名

CTGF (CTGF 产品)

别名

Ccn2 antibody, Fisp12 antibody, Hcs24 antibody, fisp-12 antibody, CCN2 antibody, HCS24 antibody, IGFBP8 antibody, NOV2 antibody, CTGRP antibody, ctgf antibody, hm:zeh1559 antibody, si:dkey-266k12.4 antibody, wu:fl25c03 antibody, zeh1559 antibody, zgc:136644 antibody, XCTGF antibody, ccn2 antibody, nov2 antibody, hcs24 antibody, igfbp8 antibody, CTGF antibody, si:ch211-173b8.2 antibody, connective tissue growth factor antibody, connective tissue growth factor a antibody, connective tissue growth factor L homeolog antibody, connective tissue growth factor b antibody, Ctgf antibody, CTGF antibody, ctgfa antibody, ctgf.L antibody, ctgf antibody, ctgfb antibody

背景

CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. And the encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

Synonyms: CCN 2 antibody|CCN family member 2 antibody|CCN2 antibody|Connective Tissue Growth Factor antibody|CTGF antibody|CTGF_HUMAN antibody|Hcs 24 antibody|Hcs24 antibody|Hypertrophic chondrocyte specific protein 24 antibody|Hypertrophic chondrocyte-specific gene product 24 antibody|Hypertrophic chondrocyte-specific protein 24 antibody|IBP-8 antibody|IGF-binding protein 8 antibody|IGFBP-8 antibody|IGFBP8 antibody|Insulin like Growth Factor Binding Protein 8 antibody|Insulin-like Growth Factor-Binding Protein 8 antibody|MGC102839 antibody|NOV 2 antibody|NOV2 antibody

基因ID

1490

UniProt

P29279

途径

Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding