M-CSF/CSF1 抗体 (AA 33-262)
-
- 抗原 See all M-CSF/CSF1 (CSF1) 抗体
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
-
抗原表位
- AA 33-262
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This M-CSF/CSF1 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse,Rat.
Gene Name: colony stimulating factor 1 (macrophage)
Protein Name: Macrophage colony-stimulating factor 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CSF1 Primary Antibody
-
-
- 应用备注
-
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
-
Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).
: "
-
Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).
-
- 抗原
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- 别名
- CSF1 (CSF1 产品)
- 别名
- CSF-1 antibody, MCSF antibody, C87615 antibody, Csfm antibody, op antibody, csf1-1 antibody, zgc:172186 antibody, CSF1 antibody, csf1-2 antibody, zgc:158436 antibody, colony stimulating factor 1 antibody, colony stimulating factor 1 (macrophage) antibody, colony stimulating factor 1a (macrophage) antibody, macrophage colony-stimulating factor 1 antibody, macrophage colony stimulating factor antibody, colony stimulating factor 1b (macrophage) antibody, CSF1 antibody, Csf1 antibody, csf1a antibody, LOC396599 antibody, LOC100860895 antibody, csf1b antibody
- 背景
-
M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Synonyms: Colony stimulating factor 1 (macrophage) antibody|Colony stimulating factor 1 antibody| Colony stimulating factor macrophage specific antibody|CSF 1 antibody|CSF-1 antibody|CSF1 antibody|CSF1_HUMAN antibody|Csfm antibody|Lanimostim antibody|M CSF antibody|M-CSF antibody|Macrophage Colony Stimulating Factor 1 antibody|Macrophage colony stimulating factor antibody|MCSF antibody|MGC31930 antibody|Processed macrophage colony-stimulating factor 1 antibody - 基因ID
- 12977
- UniProt
- P07141
- 途径
- RTK signaling
-