Claudin 2 抗体 (AA 38-230)
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- 抗原 See all Claudin 2 (CLDN2) 抗体
- Claudin 2 (CLDN2)
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抗原表位
- AA 38-230
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Claudin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Claudin-2(CLDN2) detection. Tested with WB, IHC-P in Human,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Claudin-2(CLDN2) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: claudin 2
Protein Name: Claudin-2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Claudin 2 recombinant protein (Position: A38-V230). Human Claudin 2 shares 92% amino acid (aa) sequence identity with mouse Claudin 2.
- 亚型
- IgG
- Top Product
- Discover our top product CLDN2 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for Claudin 2 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Alteration in P-glycoprotein at the blood-brain barrier in the early period of MCAO in rats." in: The Journal of pharmacy and pharmacology, Vol. 65, Issue 5, pp. 665-72, (2013) (PubMed).
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Alteration in P-glycoprotein at the blood-brain barrier in the early period of MCAO in rats." in: The Journal of pharmacy and pharmacology, Vol. 65, Issue 5, pp. 665-72, (2013) (PubMed).
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- 抗原
- Claudin 2 (CLDN2)
- 别名
- CLDN2 (CLDN2 产品)
- 别名
- CLDN2 antibody, zgc:92260 antibody, AL022813 antibody, RGD1560247 antibody, claudin 2 antibody, CLDN2 antibody, cldn2 antibody, Cldn2 antibody
- 背景
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Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.
Synonyms: Claudin-2 antibody|Claudin2 antibody|CLD2_HUMAN antibody|CLDN 2 antibody|CLDN2 antibody|OTTHUMP00000023793 antibody|SP 82 antibody|SP82 antibody - 基因ID
- 9075
- UniProt
- P57739
- 途径
- Hepatitis C
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