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Claudin 2 抗体 (AA 38-230)

CLDN2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042751
发货至: 中国
  • 抗原 See all Claudin 2 (CLDN2) 抗体
    Claudin 2 (CLDN2)
    抗原表位
    • 26
    • 12
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 38-230
    适用
    • 99
    • 19
    • 15
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 96
    • 4
    克隆类型
    • 94
    • 6
    多克隆
    标记
    • 39
    • 12
    • 10
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Claudin 2 antibody is un-conjugated
    应用范围
    • 72
    • 64
    • 49
    • 25
    • 10
    • 8
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Claudin-2(CLDN2) detection. Tested with WB, IHC-P in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Claudin-2(CLDN2) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: claudin 2
    Protein Name: Claudin-2
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Claudin 2 recombinant protein (Position: A38-V230). Human Claudin 2 shares 92% amino acid (aa) sequence identity with mouse Claudin 2.
    亚型
    IgG
    Top Product
    Discover our top product CLDN2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for Claudin 2 is approximately 0.2 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Cen, Liu, Li, He, Wang, Liu, Liu, Ji: "Alteration in P-glycoprotein at the blood-brain barrier in the early period of MCAO in rats." in: The Journal of pharmacy and pharmacology, Vol. 65, Issue 5, pp. 665-72, (2013) (PubMed).

  • 抗原
    Claudin 2 (CLDN2)
    别名
    CLDN2 (CLDN2 产品)
    别名
    CLDN2 antibody, zgc:92260 antibody, AL022813 antibody, RGD1560247 antibody, claudin 2 antibody, CLDN2 antibody, cldn2 antibody, Cldn2 antibody
    背景
    Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

    Synonyms: Claudin-2 antibody|Claudin2 antibody|CLD2_HUMAN antibody|CLDN 2 antibody|CLDN2 antibody|OTTHUMP00000023793 antibody|SP 82 antibody|SP82 antibody
    基因ID
    9075
    UniProt
    P57739
    途径
    Hepatitis C
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