CARM1 抗体 (Middle Region)
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- 抗原 See all CARM1 抗体
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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抗原表位
- AA 267-284, Middle Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Histone-arginine methyltransferase CARM1(CARM1) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- HLAPFTDEQL YMEQFTKA
- 交叉反应 (详细)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Histone-arginine methyltransferase CARM1(CARM1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: coactivator-associated arginine methyltransferase 1
Protein Name: Histone-arginine methyltransferase CARM1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PRMT4(267-284aa HLAPFTDEQLYMEQFTKA), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product CARM1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
- 别名
- CARM1 (CARM1 产品)
- 别名
- NV18905 antibody, prmt4 antibody, PRMT4 antibody, Prmt4 antibody, si:dkey-204f11.63 antibody, zgc:100805 antibody, coactivator associated arginine methyltransferase 1 antibody, coactivator associated arginine methyltransferase 1 L homeolog antibody, coactivator-associated arginine methyltransferase 1 antibody, histone-arginine methyltransferase CARM1 antibody, CARM1 antibody, carm1.L antibody, Carm1 antibody, carm1 antibody, LOC100352221 antibody
- 背景
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CARM1(coactivator-associated arginine methyltransferase 1), also known as PRMT4, is an enzyme encoded by the CARM1 gene found in human beings, as well as many other mammals. This gene is mapped to 19p13.2. CARM1 is a regulator of cyclin E1 and DHFR mRNA expression. Its main function includes catalyzing the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. CARM1 is a secondary coactivator through its association with p160 family(SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression.
Synonyms: carm1 antibody|Coactivator associated arginine methyltransferase 1 antibody|Coactivator-associated arginine methyltransferase 1 antibody|Histone arginine methyltransferase CARM 1 antibody|Histone arginine methyltransferase CARM1 antibody|Histone-arginine methyltransferase CARM1 antibody|PRMT 4 antibody|PRMT4 antibody|Protein arginine methyltransferase antibody|Protein arginine N methyltransferase 4 antibody|Protein arginine N-methyltransferase 4 antibody - UniProt
- Q86X55
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
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